Detalhe da pesquisa
1.
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity.
J Exp Med
; 204(5): 1025-36, 2007 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17470642
2.
The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis.
J Immunol
; 186(5): 2871-80, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21278342
3.
IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease.
J Immunol
; 183(1): 568-77, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19542468
4.
Genetic ablation of IRAK4 kinase activity inhibits vascular lesion formation.
Biochem Biophys Res Commun
; 367(3): 642-8, 2008 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18190779
5.
Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity.
Mol Cancer Ther
; 13(2): 364-74, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24356814
6.
Back to the Future: Therapeutic Targeting of Cancer Cell Metabolism.
SLAS Discov
; 22(4): 333-337, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28328320
7.
Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NF kappaB activation.
J Biol Chem
; 283(21): 14654-64, 2008 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18326498
8.
New class of competitive inhibitor of bacterial histidine kinases.
J Bacteriol
; 187(23): 8196-200, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16291694
9.
Essentiality of clpX, but not clpP, clpL, clpC, or clpE, in Streptococcus pneumoniae R6.
J Bacteriol
; 185(9): 2961-6, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12700276
10.
Transcriptional regulation and signature patterns revealed by microarray analyses of Streptococcus pneumoniae R6 challenged with sublethal concentrations of translation inhibitors.
J Bacteriol
; 185(1): 359-70, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12486074
11.
Global transcriptional analysis of clpP mutations of type 2 Streptococcus pneumoniae and their effects on physiology and virulence.
J Bacteriol
; 184(13): 3508-20, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12057945
12.
Constitutive expression of PcsB suppresses the requirement for the essential VicR (YycF) response regulator in Streptococcus pneumoniae R6.
Mol Microbiol
; 50(5): 1647-63, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14651645
13.
Kinetic and mechanistic analyses of new classes of inhibitors of two-component signal transduction systems using a coupled assay containing HpkA-DrrA from Thermotoga maritima.
Microbiology (Reading)
; 150(Pt 4): 885-896, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15073298
14.
Vancomycin tolerance induced by erythromycin but not by loss of vncRS, vex3, or pep27 function in Streptococcus pneumoniae.
J Bacteriol
; 184(24): 6987-7000, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12446649