Detalhe da pesquisa
1.
The magic of small structure differences in a sodium-glucose cotransporter drug discovery project-14 C-labelled drug candidates in a key-differentiating study.
J Labelled Comp Radiopharm
; 64(2): 73-76, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32633850
2.
The Keap1-Nrf2 protein-protein interaction: A suitable target for small molecules.
Drug Discov Today Technol
; 24: 11-17, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233294
3.
Characterization of RA839, a Noncovalent Small Molecule Binder to Keap1 and Selective Activator of Nrf2 Signaling.
J Biol Chem
; 290(47): 28446-28455, 2015 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26459563
4.
AVE8134, a novel potent PPARα agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic rats.
Acta Pharmacol Sin
; 33(1): 82-90, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22212431
5.
Activation of Adenosine Monophosphate-Activated Protein Kinase Reduces the Onset of Diet-Induced Hepatocellular Carcinoma in Mice.
Hepatol Commun
; 4(7): 1056-1072, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32626837
6.
Bile acid reabsorption inhibitors (BARI): novel hypolipidemic drugs.
Curr Med Chem
; 13(9): 997-1016, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16611081
7.
Multivalent glibenclamide to generate islet specific imaging probes.
Biomaterials
; 75: 1-12, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26474038
8.
Effects of AVE2268, a substituted glycopyranoside, on urinary glucose excretion and blood glucose in mice and rats.
Arzneimittelforschung
; 58(11): 574-80, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-19137908