Detalhe da pesquisa
1.
Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly.
Proc Natl Acad Sci U S A
; 117(2): 1049-1058, 2020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896582
2.
Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity.
Mol Carcinog
; 61(1): 19-32, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34610184
3.
The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile.
Int J Mol Sci
; 22(6)2021 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33805767
4.
Kröhnke pyridines: Rapid and facile access to Mcl-1 inhibitors.
Bioorg Med Chem Lett
; 28(10): 1949-1953, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29705141
5.
Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history.
Mol Biol Evol
; 32(2): 440-55, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25392342
6.
Small G proteins Rac1 and Ras regulate serine/threonine protein phosphatase 5 (PP5)·extracellular signal-regulated kinase (ERK) complexes involved in the feedback regulation of Raf1.
J Biol Chem
; 289(7): 4219-32, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24371145
7.
Membrane binding and pore formation is Ca 2+ -dependent for the Clostridioides difficile binary toxin.
bioRxiv
; 2023 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37645845
8.
Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2.
Adv Sci (Weinh)
; 10(34): e2304818, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863812
9.
Estimating side-chain order in methyl-protonated, perdeuterated proteins via multiple-quantum relaxation violated coherence transfer NMR spectroscopy.
J Biomol NMR
; 52(3): 233-43, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22314703
10.
Solution NMR evidence for symmetry in functionally or crystallographically asymmetric homodimers.
J Am Chem Soc
; 133(49): 19578-81, 2011 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22074452
11.
Simultaneous measurement of ¹H-¹5N and methyl ¹Hm-¹³Cm residual dipolar couplings in large proteins.
J Biomol NMR
; 51(1-2): 191-8, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21947927
12.
1HN, 13C, and 15N resonance assignments of the Clostridioides difficile receptor binding domain 2 (CDTb, residues 757-876).
Biomol NMR Assign
; 15(1): 35-39, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33034833
13.
An Extract of Taro (Colocasia esculenta) Mediates Potent Inhibitory Actions on Metastatic and Cancer Stem Cells by Tumor Cell-Autonomous and Immune-Dependent Mechanisms.
Breast Cancer (Auckl)
; 15: 11782234211034937, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34376983
14.
Physiologically Relevant Free Ca2+ Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6.
J Mol Biol
; 433(22): 167272, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34592217
15.
Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol
; 4(1): 299, 2021 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33674772
16.
Alanine methyl groups as NMR probes of molecular structure and dynamics in high-molecular-weight proteins.
J Am Chem Soc
; 132(51): 18340-50, 2010 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21138300
17.
High resolution measurement of methyl 13C(m)-13C and 1H(m)-13C(m) residual dipolar couplings in large proteins.
J Am Chem Soc
; 132(40): 13984-7, 2010 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20860373
18.
Variation in quadrupole couplings of alpha deuterons in ubiquitin suggests the presence of C(alpha)-H(alpha)...O=C hydrogen bonds.
J Am Chem Soc
; 132(22): 7709-19, 2010 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20476744
19.
Correction to: 1HN, 13C, and 15N resonance assignments of human calmodulin bound to a peptide derived from the STRA6 vitamin A transporter (CaMBP2).
Biomol NMR Assign
; 14(2): 347, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32248334
20.
1HN, 13C, and 15N resonance assignments of human calmodulin bound to a peptide derived from the STRA6 vitamin A transporter (CaMBP2).
Biomol NMR Assign
; 13(2): 275-278, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30875027