Detalhe da pesquisa
1.
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress.
Proc Natl Acad Sci U S A
; 121(10): e2313540121, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38416681
2.
Proteomic Profiling of Mitochondrial-Derived Vesicles in Brain Reveals Enrichment of Respiratory Complex Sub-assemblies and Small TIM Chaperones.
J Proteome Res
; 20(1): 506-517, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242952
3.
The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons.
Res Sq
; 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38562709
4.
The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons.
bioRxiv
; 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38014143
5.
Hallmarks and Molecular Tools for the Study of Mitophagy in Parkinson's Disease.
Cells
; 11(13)2022 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35805181
6.
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.
Autophagy
; 17(12): 4363-4385, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34030589
7.
Nuclear TP53: An unraveled function as transcriptional repressor of PINK1.
Autophagy
; 14(6): 1099-1101, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29749796
8.
Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation.
Cell Death Differ
; 25(5): 873-884, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29352272
9.
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.
Elife
; 72018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29676259
10.
ß-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.
Biol Psychiatry
; 83(5): 416-427, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28587718
11.
Presenilins at the crossroad of a functional interplay between PARK2/PARKIN and PINK1 to control mitophagy: Implication for neurodegenerative diseases.
Autophagy
; 13(11): 2004-2005, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28914586
12.
Extracellular protein degradation via the lysosome.
Commun Chem
; 3(1): 149, 2020 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36703340
13.
Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells.
Oncotarget
; 6(17): 15652-61, 2015 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26002551
14.
Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.
J Mol Cell Biol
; 5(2): 132-42, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359614