Detalhe da pesquisa
1.
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
Antimicrob Agents Chemother
; 68(4): e0137323, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38380945
2.
Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi® and Epclusa®.
Bioorg Med Chem Lett
; 29(16): 2415-2427, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31230974
3.
In Vitro Antiviral Activity and Resistance Profile Characterization of the Hepatitis C Virus NS5A Inhibitor Ledipasvir.
Antimicrob Agents Chemother
; 60(3): 1847-1853, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26824950
4.
Robust and persistent replication of the genotype 6a hepatitis C virus replicon in cell culture.
Antimicrob Agents Chemother
; 58(5): 2638-46, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550344
5.
A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.
Nat Genet
; 33(4): 508-13, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12652302
6.
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro.
Sci Rep
; 13(1): 3131, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36823196
7.
In vitro efficacy of approved and experimental antivirals against novel genotype 3 hepatitis C virus subgenomic replicons.
Antiviral Res
; 100(2): 439-45, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24013001
8.
High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888.
PLoS One
; 6(3): e17692, 2011 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21408192
9.
Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth.
Cancer Cell
; 17(4): 388-99, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385363
10.
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched.
Cell
; 111(1): 63-75, 2002 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-12372301
11.
Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.
Mol Cell
; 12(5): 1261-74, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14636583