1.
Mult Scler
; 22(14): 1888-1890, 2016 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27207455
RESUMO
BACKGROUND: The appearance of solid tumors und lymphomas during treatment with fingolimod was observed in studies and has been described in case reports. OBJECTIVE: To report a case of primary cutaneous CD30(+) anaplastic large-cell T-cell lymphoma during treatment of multiple sclerosis (MS) with fingolimod. METHODS: Case study. RESULTS: Our patient developed a lymphoma a few weeks after initialization of therapy with fingolimod; 5 weeks after discontinuation of treatment the lesions resolved. CONCLUSION: Causality of fingolimod is indicated by the fact that the skin lesions appeared after commencement of treatment and resolved after discontinuation of therapy. This case serves as a reminder of the potential side effects of fingolimod.
Assuntos
Cloridrato de Fingolimode/efeitos adversos , Imunossupressores/efeitos adversos , Antígeno Ki-1 , Linfoma Anaplásico de Células Grandes/induzido quimicamente , Esclerose Múltipla/tratamento farmacológico , Neoplasias Cutâneas/induzido quimicamente , Feminino , Humanos , Pessoa de Meia-Idade
2.
J Dtsch Dermatol Ges
; 13(3): 249-51, 2015 Mar.
Artigo
em Inglês, Alemão
| MEDLINE
| ID: mdl-25706298