Detalhe da pesquisa
1.
The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B12.
Cell
; 171(4): 771-782.e11, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29056341
2.
Congenital Hypermetabolism and Uncoupled Oxidative Phosphorylation.
N Engl J Med
; 387(15): 1395-1403, 2022 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239646
3.
MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations.
Nucleic Acids Res
; 49(D1): D1541-D1547, 2021 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33174596
4.
Architecture of the mitochondrial calcium uniporter.
Nature
; 533(7602): 269-73, 2016 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27135929
5.
Crystal structure of MICU2 and comparison with MICU1 reveal insights into the uniporter gating mechanism.
Proc Natl Acad Sci U S A
; 116(9): 3546-3555, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30755530
6.
MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca2+ and Mn2+.
Proc Natl Acad Sci U S A
; 115(34): E7960-E7969, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082385
7.
A genetically encoded tool for manipulation of NADP+/NADPH in living cells.
Nat Chem Biol
; 13(10): 1088-1095, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28805804
8.
High-affinity cooperative Ca2+ binding by MICU1-MICU2 serves as an on-off switch for the uniporter.
EMBO Rep
; 18(8): 1397-1411, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28615291
9.
CLYBL is a polymorphic human enzyme with malate synthase and ß-methylmalate synthase activity.
Hum Mol Genet
; 23(9): 2313-23, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24334609
10.
The green tea polyphenol (-)-epigallocatechin-3-gallate inhibits magnesium binding to the C-domain of cardiac troponin C.
J Muscle Res Cell Motil
; 34(2): 107-13, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23417789
11.
John Gergely (1919-2013): a pillar in the muscle protein field.
J Muscle Res Cell Motil
; 34(5-6): 441-6, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24264290
12.
The mitochondrial calcium uniporter transports Ca 2+ via a ligand-relay mechanism.
bioRxiv
; 2023 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398228
13.
X-ray structures of magnesium and manganese complexes with the N-terminal domain of calmodulin: insights into the mechanism and specificity of metal ion binding to an EF-hand.
Biochemistry
; 51(31): 6182-94, 2012 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22803592
14.
Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins.
Biochim Biophys Acta
; 1813(5): 913-21, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21262274
15.
Differential effects of caldesmon on the intermediate conformational states of polymerizing actin.
J Biol Chem
; 285(1): 71-9, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19889635
16.
The Ca2+/Mg2+ sites of troponin C modulate crossbridge-mediated thin filament activation in cardiac myofibrils.
Biochem Biophys Res Commun
; 408(4): 697-700, 2011 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21539814
17.
Modular structure of smooth muscle Myosin light chain kinase: hydrodynamic modeling and functional implications.
Biochemistry
; 49(13): 2903-17, 2010 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20196616
18.
Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma.
Cancer Cell
; 34(2): 242-255.e5, 2018 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30107175
19.
Structural basis for diversity of the EF-hand calcium-binding proteins.
J Mol Biol
; 359(3): 509-25, 2006 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16678204
20.
Structure of a trapped intermediate of calmodulin: calcium regulation of EF-hand proteins from a new perspective.
J Mol Biol
; 346(5): 1351-66, 2005 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15713486