RESUMO
The umbilical cord is exposed to a great variety of injuries and events throughout the pregnancy whose origin may be either structural, mechanical, hamartomatous or infectious (1). Some of these alterations unquestionably interfere directly with the fetoplacental circulation either blocking it or creating severe haemorrhage as a result of laceration or tumor rupture. True tumors of the umbilical cord interfere directly with the fetal development. Two true tumors of the umbilical cord are described in this paper: chorangioma and teratoma. Chorangioma is a benign tumor, but has a very high rate of rate of perinatal mortality. Its frequency is rare, reporting in literature it presence of 1:3500 pregnancies. Our objective was to review world-wide literature and to report a case of fetal death by chorangioma of umbilical cord.
Assuntos
Âmnio , Doenças Fetais , Hemangioma/complicações , Hemorragia/complicações , Cordão Umbilical , Adolescente , Feminino , Morte Fetal , Humanos , Gravidez , Ruptura EspontâneaRESUMO
We analyzed a 20 year-old patient case exposed in utero to diethylstilbestrol, as probably predisposed factor in vaginal cancer. The histopathological report of the incisional biopsy was clear cell vaginal adenocarcinoma, stage III, widespread to the pelvic wall, with metastasis to regional lymph nodes, and lack of distant metastasis. We decided surgical management: protocolized laparotomy, peritoneal washing, retroperitoneal node biopsies and a radical hysterectomy, Piver III, with two thirds parts of vagina. By poor prognosis we decided to offer an adjuvant management, with systemic chemotherapy.