Detalhe da pesquisa
1.
The future of stem cell therapies for Parkinson disease.
Nat Rev Neurosci
; 21(2): 103-115, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31907406
2.
Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli.
Brain
; 140(3): 692-706, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28115364
3.
Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism.
Proc Natl Acad Sci U S A
; 110(46): E4375-84, 2013 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24170862
4.
Generation of induced neurons via direct conversion in vivo.
Proc Natl Acad Sci U S A
; 110(17): 7038-43, 2013 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23530235
5.
The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease.
Brain
; 133(Pt 2): 482-95, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20123725
6.
Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson's disease.
Eur J Neurosci
; 31(12): 2266-78, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20529122
7.
Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain.
Eur J Neurosci
; 30(4): 625-38, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19674082
8.
hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease.
Cell Rep
; 28(13): 3462-3473.e5, 2019 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31553914
9.
Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats.
J Comp Neurol
; 526(13): 2133-2146, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30007046
10.
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells.
Stem Cell Reports
; 9(4): 1207-1220, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28943253
11.
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.
Cell Stem Cell
; 20(1): 135-148, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28094017
12.
Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair.
Cell Stem Cell
; 19(6): 679-680, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27912087
13.
In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry.
Cell Rep
; 12(3): 474-81, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26166567
14.
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.
Stem Cell Reports
; 4(6): 975-83, 2015 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26004633
15.
Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain.
Sci Rep
; 4: 6330, 2014 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25208484
16.
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.
Cell Stem Cell
; 15(5): 653-65, 2014 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25517469
17.
Human foetal brain tissue as quality control when developing stem cells towards cell replacement therapy for neurological diseases.
Neuroreport
; 24(18): 1025-30, 2013 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24257249
18.
Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions.
Cell Rep
; 1(6): 703-14, 2012 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22813745
19.
GDNF is not required for catecholaminergic neuron survival in vivo.
Nat Neurosci
; 18(3): 319-22, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25710828
20.
Unilateral axonal or terminal injection of 6-hydroxydopamine causes rapid-onset nigrostriatal degeneration and contralateral motor impairments in the rat.
Brain Res Bull
; 77(5): 312-9, 2008 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18817852