Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Sublethal cytochrome c release generates drug-tolerant persister cells.

Kalkavan, Halime; Chen, Mark J; Crawford, Jeremy C; Quarato, Giovanni; Fitzgerald, Patrick; Tait, Stephen W G; Goding, Colin R; Green, Douglas R.

Cell ; 185(18): 3356-3374.e22, 2022 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-36055199

2.

Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral T_reg cell differentiation.

Lin, Liangyu; Hu, Mingyuan; Li, Qing; Du, Liming; Lin, Li; Xue, Yueqing; Zheng, Fanjun; Wang, Fei; Liu, Keli; Wang, Yu; Ye, Jiayin; Jiang, Xu; Wang, Xuefeng; Wang, Jiaqi; Zhai, Jingjie; Liu, Benming; Xie, Hongzhen; You, Yanqin; Wang, Jinyong; Kong, Xiangyin; Feng, Dechun; Green, Douglas R; Shi, Yufang; Wang, Ying.

Nat Immunol ; 25(1): 54-65, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38062135

3.

Polyamine metabolism is a central determinant of helper T cell lineage fidelity.

Puleston, Daniel J; Baixauli, Francesc; Sanin, David E; Edwards-Hicks, Joy; Villa, Matteo; Kabat, Agnieszka M; Kaminski, Marcin M; Stanckzak, Michal; Weiss, Hauke J; Grzes, Katarzyna M; Piletic, Klara; Field, Cameron S; Corrado, Mauro; Haessler, Fabian; Wang, Chao; Musa, Yaarub; Schimmelpfennig, Lena; Flachsmann, Lea; Mittler, Gerhard; Yosef, Nir; Kuchroo, Vijay K; Buescher, Joerg M; Balabanov, Stefan; Pearce, Edward J; Green, Douglas R; Pearce, Erika L.

Cell ; 184(16): 4186-4202.e20, 2021 08 05.

Artigo em Inglês | MEDLINE | ID: mdl-34216540

4.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.

Zhang, Ting; Yin, Chaoran; Boyd, David F; Quarato, Giovanni; Ingram, Justin P; Shubina, Maria; Ragan, Katherine B; Ishizuka, Takumi; Crawford, Jeremy Chase; Tummers, Bart; Rodriguez, Diego A; Xue, Jia; Peri, Suraj; Kaiser, William J; López, Carolina B; Xu, Yan; Upton, Jason W; Thomas, Paul G; Green, Douglas R; Balachandran, Siddharth.

Cell ; 180(6): 1115-1129.e13, 2020 03 19.

Artigo em Inglês | MEDLINE | ID: mdl-32200799

5.

The Coming Decade of Cell Death Research: Five Riddles.

Green, Douglas R.

Cell ; 177(5): 1094-1107, 2019 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-31100266

6.

Autophagy-Independent Functions of the Autophagy Machinery.

Galluzzi, Lorenzo; Green, Douglas R.

Cell ; 177(7): 1682-1699, 2019 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-31199916

7.

LC3-Associated Endocytosis Facilitates ß-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

Heckmann, Bradlee L; Teubner, Brett J W; Tummers, Bart; Boada-Romero, Emilio; Harris, Lacie; Yang, Mao; Guy, Clifford S; Zakharenko, Stanislav S; Green, Douglas R.

Cell ; 178(3): 536-551.e14, 2019 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-31257024

8.

An Element of Life.

Green, Douglas R.

Cell ; 172(3): 389-390, 2018 01 25.

Artigo em Inglês | MEDLINE | ID: mdl-29373826

9.

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

Cunha, Larissa D; Yang, Mao; Carter, Robert; Guy, Clifford; Harris, Lacie; Crawford, Jeremy C; Quarato, Giovanni; Boada-Romero, Emilio; Kalkavan, Halime; Johnson, Michael D L; Natarajan, Sivaraman; Turnis, Meghan E; Finkelstein, David; Opferman, Joseph T; Gawad, Charles; Green, Douglas R.

Cell ; 175(2): 429-441.e16, 2018 10 04.

Artigo em Inglês | MEDLINE | ID: mdl-30245008

10.

Loss of CD4⁺ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

West, Erin E; Merle, Nicolas S; Kaminski, Marcin M; Palacios, Gustavo; Kumar, Dhaneshwar; Wang, Luopin; Bibby, Jack A; Overdahl, Kirsten; Jarmusch, Alan K; Freeley, Simon; Lee, Duck-Yeon; Thompson, J Will; Yu, Zu-Xi; Taylor, Naomi; Sitbon, Marc; Green, Douglas R; Bohrer, Andrea; Mayer-Barber, Katrin D; Afzali, Behdad; Kazemian, Majid; Scholl-Buergi, Sabine; Karall, Daniela; Huemer, Martina; Kemper, Claudia.

Immunity ; 56(9): 2036-2053.e12, 2023 09 12.

Artigo em Inglês | MEDLINE | ID: mdl-37572656

11.

The clearance of dead cells by efferocytosis.

Boada-Romero, Emilio; Martinez, Jennifer; Heckmann, Bradlee L; Green, Douglas R.

Nat Rev Mol Cell Biol ; 21(7): 398-414, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32251387

12.

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences.

Gong, Yi-Nan; Guy, Cliff; Olauson, Hannes; Becker, Jan Ulrich; Yang, Mao; Fitzgerald, Patrick; Linkermann, Andreas; Green, Douglas R.

Cell ; 169(2): 286-300.e16, 2017 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-28388412

13.

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

Moretti, Julien; Roy, Soumit; Bozec, Dominique; Martinez, Jennifer; Chapman, Jessica R; Ueberheide, Beatrix; Lamming, Dudley W; Chen, Zhijian J; Horng, Tiffany; Yeretssian, Garabet; Green, Douglas R; Blander, J Magarian.

Cell ; 171(4): 809-823.e13, 2017 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-29056340

14.

A BH3 Mimetic for Killing Cancer Cells.

Green, Douglas R.

Cell ; 165(7): 1560, 2016 Jun 16.

Artigo em Inglês | MEDLINE | ID: mdl-27315468

15.

BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation.

Llambi, Fabien; Wang, Yue-Ming; Victor, Bernadette; Yang, Mao; Schneider, Desiree M; Gingras, Sébastien; Parsons, Melissa J; Zheng, Janet H; Brown, Scott A; Pelletier, Stéphane; Moldoveanu, Tudor; Chen, Taosheng; Green, Douglas R.

Cell ; 165(2): 421-33, 2016 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-26949185

16.

LC3-Associated Endocytosis Facilitates ß-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

Heckmann, Bradlee L; Teubner, Brett J W; Tummers, Bart; Boada-Romero, Emilio; Harris, Lacie; Yang, Mao; Guy, Clifford S; Zakharenko, Stanislav S; Green, Douglas R.

Cell ; 183(6): 1733-1734, 2020 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-33306957

17.

Necroptosis blockade prevents lung injury in severe influenza.

Gautam, Avishekh; Boyd, David F; Nikhar, Sameer; Zhang, Ting; Siokas, Ioannis; Van de Velde, Lee-Ann; Gaevert, Jessica; Meliopoulos, Victoria; Thapa, Bikash; Rodriguez, Diego A; Cai, Kathy Q; Yin, Chaoran; Schnepf, Daniel; Beer, Julius; DeAntoneo, Carly; Williams, Riley M; Shubina, Maria; Livingston, Brandi; Zhang, Dingqiang; Andrake, Mark D; Lee, Seungheon; Boda, Raghavender; Duddupudi, Anantha L; Crawford, Jeremy Chase; Vogel, Peter; Loch, Christian; Schwemmle, Martin; Fritz, Lawrence C; Schultz-Cherry, Stacey; Green, Douglas R; Cuny, Gregory D; Thomas, Paul G; Degterev, Alexei; Balachandran, Siddharth.

Nature ; 628(8009): 835-843, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38600381

18.

Localization of a TORC1-eIF4F translation complex during CD8⁺ T cell activation drives divergent cell fate.

Liedmann, Swantje; Liu, Xueyan; Guy, Clifford S; Crawford, Jeremy Chase; Rodriguez, Diego A; Kuzuoglu-Öztürk, Duygu; Guo, Ao; Verbist, Katherine C; Temirov, Jamshid; Chen, Mark J; Ruggero, Davide; Zhang, Hui; Thomas, Paul G; Green, Douglas R.

Mol Cell ; 82(13): 2401-2414.e9, 2022 07 07.

Artigo em Inglês | MEDLINE | ID: mdl-35597236

19.

The evolution of regulated cell death pathways in animals and their evasion by pathogens.

Tummers, Bart; Green, Douglas R.

Physiol Rev ; 102(1): 411-454, 2022 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-34898294

20.

Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.

Tummers, Bart; Mari, Luigi; Guy, Clifford S; Heckmann, Bradlee L; Rodriguez, Diego A; Rühl, Sebastian; Moretti, Julien; Crawford, Jeremy Chase; Fitzgerald, Patrick; Kanneganti, Thirumala-Devi; Janke, Laura J; Pelletier, Stephane; Blander, J Magarian; Green, Douglas R.

Immunity ; 52(6): 994-1006.e8, 2020 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-32428502

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Sublethal cytochrome c release generates drug-tolerant persister cells.

Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral T_reg cell differentiation.

Polyamine metabolism is a central determinant of helper T cell lineage fidelity.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.

The Coming Decade of Cell Death Research: Five Riddles.

Autophagy-Independent Functions of the Autophagy Machinery.

LC3-Associated Endocytosis Facilitates ß-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

An Element of Life.

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

Loss of CD4⁺ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

The clearance of dead cells by efferocytosis.

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences.

STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum.

A BH3 Mimetic for Killing Cancer Cells.

BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation.

LC3-Associated Endocytosis Facilitates ß-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

Necroptosis blockade prevents lung injury in severe influenza.

Localization of a TORC1-eIF4F translation complex during CD8⁺ T cell activation drives divergent cell fate.

The evolution of regulated cell death pathways in animals and their evasion by pathogens.

Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis.