Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A Survey of Recently Discovered Naturally Occurring Organohalogen Compounds.

Gribble, Gordon W.

J Nat Prod ; 87(4): 1285-1305, 2024 Apr 26.

Artigo em Inglês | MEDLINE | ID: mdl-38375796

2.

The Generation of Indole-2,3-quinodimethanes from the Deamination of 1,2,3,4-Tetrahydropyrrolo[3,4-b]indoles.

Rinderspacher, Alison; Gribble, Gordon W.

Molecules ; 25(2)2020 Jan 09.

Artigo em Inglês | MEDLINE | ID: mdl-31936442

3.

First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors.

Li, Yangxiong; Gardner, Jessi J; Fortney, Katherine R; Leus, Inga V; Bonifay, Vincent; Zgurskaya, Helen I; Pletnev, Alexandre A; Zhang, Sheng; Zhang, Zhong-Yin; Gribble, Gordon W; Spinola, Stanley M; Duerfeldt, Adam S.

Bioorg Med Chem Lett ; 29(14): 1836-1841, 2019 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-31104993

4.

A Modified ToxT Inhibitor Reduces Vibrio cholerae Virulence in Vivo.

Woodbrey, Anne K; Onyango, Evans O; Kovacikova, Gabriela; Kull, F Jon; Gribble, Gordon W.

Biochemistry ; 57(38): 5609-5615, 2018 09 25.

Artigo em Inglês | MEDLINE | ID: mdl-30160100

5.

Design, synthesis, and biological activity of second-generation synthetic oleanane triterpenoids.

Fu, Liangfeng; Lin, Qi-Xian; Onyango, Evans O; Liby, Karen T; Sporn, Michael B; Gribble, Gordon W.

Org Biomol Chem ; 15(28): 6001-6005, 2017 Jul 19.

Artigo em Inglês | MEDLINE | ID: mdl-28678272

6.

Synthesis of a Masked 2,3-Diaminoindole.

Mannes, Philip Z; Onyango, Evans O; Gribble, Gordon W.

J Org Chem ; 81(24): 12478-12481, 2016 12 16.

Artigo em Inglês | MEDLINE | ID: mdl-27978742

7.

Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.

Cao, Martine; Onyango, Evans O; Williams, Charlotte R; Royce, Darlene B; Gribble, Gordon W; Sporn, Michael B; Liby, Karen T.

Pharmacol Res ; 100: 135-47, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-26238177

8.

Triple Benzannulation of Naphthalene via a 1,3,6-Naphthotriyne Synthetic Equivalent. Synthesis of Dibenz[a,c]anthracene.

Mannes, Philip Z; Onyango, Evans O; Gribble, Gordon W.

J Org Chem ; 80(21): 11189-92, 2015 Nov 06.

Artigo em Inglês | MEDLINE | ID: mdl-26452053

9.

Syntheses of 1-Bromo-8-methylnaphthalene and 1-Bromo-5-methylnaphthalene.

Onyango, Evans O; Kelley, Anne R; Qian, David C; Gribble, Gordon W.

J Org Chem ; 80(11): 5970-2, 2015 Jun 05.

Artigo em Inglês | MEDLINE | ID: mdl-25923236

10.

Biological Activity of Recently Discovered Halogenated Marine Natural Products.

Gribble, Gordon W.

Mar Drugs ; 13(7): 4044-136, 2015 Jun 30.

Artigo em Inglês | MEDLINE | ID: mdl-26133553

11.

Synthesis and biological evaluation of amino acid methyl ester conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid against the production of nitric oxide (NO).

Onyango, Evans O; Fu, Liangfeng; Cao, Martine; Liby, Karen T; Sporn, Michael B; Gribble, Gordon W.

Bioorg Med Chem Lett ; 24(2): 532-4, 2014 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-24388806

12.

An efficient synthesis of methyl 2-cyano-3,12-dioxoursol-1,9-dien-28-oate (CDDU-methyl ester): analogues, biological activities, and comparison with oleanolic acid derivatives.

Fu, Liangfeng; Lin, Qi-Xian; Liby, Karen T; Sporn, Michael B; Gribble, Gordon W.

Org Biomol Chem ; 12(28): 5192-200, 2014 Jul 28.

Artigo em Inglês | MEDLINE | ID: mdl-24915424

13.

Methyl 1-benzyl-5-methyl-2,4-diphenyl-1H-pyrrole-3-carboxyl-ate.

Lopchuk, Justin M; Gribble, Gordon W; Jasinski, Jerry P.

Acta Crystallogr Sect E Struct Rep Online ; 70(Pt 3): o338-9, 2014 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-24765032

14.

Bruceolline D: 3,3-dimethyl-1H,4H-cyclo-penta-[b]indol-2(3H)-one.

Lopchuk, Justin M; Gribble, Gordon W; Jasinski, Jerry P.

Acta Crystallogr Sect E Struct Rep Online ; 69(Pt 7): o1043, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24046619

15.

Bruceolline J: 2-hy-droxy-3,3-dimethyl-2,3-di-hydro-cyclo-penta-[b]indol-1(4H)-one.

Lopchuk, Justin M; Gribble, Gordon W; Millikan, Sean P; Jasinski, Jerry P.

Acta Crystallogr Sect E Struct Rep Online ; 69(Pt 8): o1351-2, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24109417

16.

Naturally Occurring Organohalogen Compounds-A Comprehensive Review.

Gribble, Gordon W.

Prog Chem Org Nat Prod ; 121: 1-546, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37488466

17.

3,3-Dimethyl-1,2,3,4-tetra-hydro-cyclo-penta-[b]indole-1,2-dione (bruceolline E).

Jordon, Jason A; Badenock, Jeanese C; Gribble, Gordon W; Jasinski, Jerry P; Golen, James A.

Acta Crystallogr Sect E Struct Rep Online ; 68(Pt 2): o364-5, 2012 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-22346990

18.

Probing binding determinants in center P of the cytochrome bc(1) complex using novel hydroxy-naphthoquinones.

Hughes, Louise M; Covian, Raul; Gribble, Gordon W; Trumpower, Bernard L.

Biochim Biophys Acta ; 1797(1): 38-43, 2010 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-19660431

19.

New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress.

Sporn, Michael B; Liby, Karen T; Yore, Mark M; Fu, Liangfeng; Lopchuk, Justin M; Gribble, Gordon W.

J Nat Prod ; 74(3): 537-45, 2011 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-21309592

20.

Correction to "Triple Benzannulation of Naphthalene via a 1,3,6-Naphthotriyne Synthetic Equivalent. Synthesis of Dibenz[a,c]anthracene".

Mannes, Philip Z; Onyango, Evans O; Gribble, Gordon W.

J Org Chem ; 80(24): 12746, 2015 Dec 18.

Artigo em Inglês | MEDLINE | ID: mdl-26600209

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A Survey of Recently Discovered Naturally Occurring Organohalogen Compounds.

The Generation of Indole-2,3-quinodimethanes from the Deamination of 1,2,3,4-Tetrahydropyrrolo[3,4-b]indoles.

First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors.

A Modified ToxT Inhibitor Reduces Vibrio cholerae Virulence in Vivo.

Design, synthesis, and biological activity of second-generation synthetic oleanane triterpenoids.

Synthesis of a Masked 2,3-Diaminoindole.

Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.

Triple Benzannulation of Naphthalene via a 1,3,6-Naphthotriyne Synthetic Equivalent. Synthesis of Dibenz[a,c]anthracene.

Syntheses of 1-Bromo-8-methylnaphthalene and 1-Bromo-5-methylnaphthalene.

Biological Activity of Recently Discovered Halogenated Marine Natural Products.

Synthesis and biological evaluation of amino acid methyl ester conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid against the production of nitric oxide (NO).

An efficient synthesis of methyl 2-cyano-3,12-dioxoursol-1,9-dien-28-oate (CDDU-methyl ester): analogues, biological activities, and comparison with oleanolic acid derivatives.

Methyl 1-benzyl-5-methyl-2,4-diphenyl-1H-pyrrole-3-carboxyl-ate.

Bruceolline D: 3,3-dimethyl-1H,4H-cyclo-penta-[b]indol-2(3H)-one.

Bruceolline J: 2-hy-droxy-3,3-dimethyl-2,3-di-hydro-cyclo-penta-[b]indol-1(4H)-one.

Naturally Occurring Organohalogen Compounds-A Comprehensive Review.

3,3-Dimethyl-1,2,3,4-tetra-hydro-cyclo-penta-[b]indole-1,2-dione (bruceolline E).

Probing binding determinants in center P of the cytochrome bc(1) complex using novel hydroxy-naphthoquinones.

New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress.

Correction to "Triple Benzannulation of Naphthalene via a 1,3,6-Naphthotriyne Synthetic Equivalent. Synthesis of Dibenz[a,c]anthracene".