Detalhe da pesquisa
1.
Ethanol inhibits pancreatic acinar cell autophagy through upregulation of ATG4B, mediating pathological responses of alcoholic pancreatitis.
Am J Physiol Gastrointest Liver Physiol
; 325(3): G265-G278, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37431575
2.
Critical thresholds: key to unlocking the door to the prevention and specific treatments for acute pancreatitis.
Gut
; 70(1): 194-203, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973069
3.
Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice.
Cell Mol Life Sci
; 77(9): 1811-1825, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363815
4.
Acute Pancreatitis: A Multifaceted Set of Organelle and Cellular Interactions.
Gastroenterology
; 156(7): 1941-1950, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30660726
5.
Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.
Gastroenterology
; 154(3): 689-703, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29074451
6.
Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.
Gastroenterology
; 154(3): 704-718.e10, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29079517
7.
Acute acinar pancreatitis blocks vesicle-associated membrane protein 8 (VAMP8)-dependent secretion, resulting in intracellular trypsin accumulation.
J Biol Chem
; 292(19): 7828-7839, 2017 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28242757
8.
Autophagy, Inflammation, and Immune Dysfunction in the Pathogenesis of Pancreatitis.
Gastroenterology
; 153(5): 1212-1226, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28918190
9.
Human Pancreatic Acinar Cells: Proteomic Characterization, Physiologic Responses, and Organellar Disorders in ex Vivo Pancreatitis.
Am J Pathol
; 187(12): 2726-2743, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28935577
10.
Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges.
Am J Physiol Gastrointest Liver Physiol
; 313(5): G524-G536, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28705806
11.
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP.
Gut
; 65(8): 1333-46, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26071131
12.
New insights into the pathways initiating and driving pancreatitis.
Curr Opin Gastroenterol
; 32(5): 429-435, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27428704
13.
Inflammation, autophagy, and obesity: common features in the pathogenesis of pancreatitis and pancreatic cancer.
Gastroenterology
; 144(6): 1199-209.e4, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23622129
14.
Effects of oxidative alcohol metabolism on the mitochondrial permeability transition pore and necrosis in a mouse model of alcoholic pancreatitis.
Gastroenterology
; 144(2): 437-446.e6, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23103769
15.
The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation.
Gastroenterology
; 142(2): 377-87.e1-5, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22044669
16.
NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox.
J Biol Chem
; 286(10): 7779-7787, 2011 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21118808
17.
Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells.
Biochim Biophys Acta
; 1813(8): 1465-74, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21596068
18.
Autophagy and pancreatitis.
Am J Physiol Gastrointest Liver Physiol
; 303(9): G993-G1003, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22961802
19.
The burning question: why is smoking a risk factor for pancreatic cancer?
Pancreatology
; 12(4): 344-9, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22898636
20.
Impaired autophagy and organellar dysfunction in pancreatitis.
J Gastroenterol Hepatol
; 27 Suppl 2: 27-32, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22320913