Detalhe da pesquisa
1.
cGAS-STING drives ageing-related inflammation and neurodegeneration.
Nature
; 620(7973): 374-380, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37532932
2.
The cGAS-STING pathway drives type I IFN immunopathology in COVID-19.
Nature
; 603(7899): 145-151, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35045565
3.
Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability.
Immunity
; 43(4): 727-38, 2015 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26431948
4.
Targeting STING with covalent small-molecule inhibitors.
Nature
; 559(7713): 269-273, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29973723
5.
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation.
Nat Immunol
; 12(9): 844-52, 2011 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822257
6.
Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance.
Immunity
; 37(5): 800-12, 2012 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142783
7.
EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis.
PLoS Pathog
; 14(12): e1007491, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30571761
8.
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation.
Immunity
; 32(1): 54-66, 2010 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20060329
9.
Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.
Gastroenterology
; 149(7): 1860-1871.e8, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26344057
10.
SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens.
PLoS Pathog
; 9(8): e1003539, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23950714
11.
Cutting edge: TNF receptor-associated factor 4 restricts IL-17-mediated pathology and signaling processes.
J Immunol
; 189(1): 33-7, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22649194
12.
Protective role of macrophage-derived ceruloplasmin in inflammatory bowel disease.
Gut
; 62(2): 209-19, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22345661
13.
Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Gastroenterology
; 139(2): 574-85, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20416302
14.
IRAK4 kinase activity is required for Th17 differentiation and Th17-mediated disease.
J Immunol
; 183(1): 568-77, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19542468
15.
The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response.
J Immunol
; 182(5): 2601-9, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19234154
16.
m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner.
Open Biol
; 11(3): 210030, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33715389
17.
Signalling strength determines proapoptotic functions of STING.
Nat Commun
; 8(1): 427, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874664
18.
Inside Job: Viruses Transfer cGAMP between Cells.
Cell Host Microbe
; 18(3): 263-5, 2015 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26355209
19.
Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.
Cell Host Microbe
; 17(6): 799-810, 2015 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26048138
20.
IKKα negatively regulates ASC-dependent inflammasome activation.
Nat Commun
; 5: 4977, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25266676