Detalhe da pesquisa
1.
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Nature
; 508(7495): 215-21, 2014 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24695224
2.
Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.
Nature
; 544(7651): 508, 2017 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28447629
3.
A Drosophila female pheromone elicits species-specific long-range attraction via an olfactory channel with dual specificity for sex and food.
BMC Biol
; 15(1): 88, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28962619
4.
High-affinity recognition of the human C-reactive protein independent of phosphocholine.
Org Biomol Chem
; 15(21): 4644-4654, 2017 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28513744
5.
Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei.
J Biol Chem
; 288(38): 27456-27468, 2013 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23900839
6.
Immunomodulatory activity of commonly used drugs on Fc-receptor-mediated human natural killer cell activation.
Cancer Immunol Immunother
; 63(6): 627-41, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24682538
7.
Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy.
Autophagy
; 18(7): 1486-1502, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34740308
8.
Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound.
Cell Death Dis
; 12(10): 914, 2021 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34615851
9.
In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization.
Front Chem
; 8: 443, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32548091
10.
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy.
Nat Commun
; 11(1): 1308, 2020 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32161261
11.
Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability.
J Med Chem
; 63(8): 3915-3934, 2020 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32212728
12.
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Nat Commun
; 10(1): 5050, 2019 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31676755
13.
Identification of inhibitors of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity by small-molecule screening.
Chem Biol Drug Des
; 92(1): 1255-1271, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29500863
14.
Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions.
Cell Chem Biol
; 25(2): 224-229.e2, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29276046
15.
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.
Nat Commun
; 9(1): 250, 2018 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29343827
16.
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun
; 14(1): 5019, 2023 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596290
17.
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun
; 9(1): 1107, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29549331
18.
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun
; 9(1): 2071, 2018 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29789663
19.
dUTPase inhibition augments replication defects of 5-Fluorouracil.
Oncotarget
; 8(14): 23713-23726, 2017 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28423595
20.
Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.
Cancer Res
; 77(7): 1741-1752, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28087597