Detalhe da pesquisa
1.
Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity.
Nat Immunol
; 23(4): 568-580, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314846
2.
Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease.
Neurobiol Dis
; 177: 105969, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36535551
3.
Domain Organization of Lentiviral and Betaretroviral Surface Envelope Glycoproteins Modeled with AlphaFold.
J Virol
; 96(2): e0134821, 2022 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34705555
4.
Deep-Time Structural Evolution of Retroviral and Filoviral Surface Envelope Proteins.
J Virol
; 96(7): e0006322, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35319227
5.
Using a peptide-based mass spectrometry approach to quantitate proteolysis of an intact heterogeneous procollagen substrate by BMP1 for antagonistic antibody screening.
Anal Bioanal Chem
; 414(22): 6601-6610, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35821276
6.
Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts.
Am J Physiol Cell Physiol
; 320(2): C162-C174, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33206546
7.
Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS.
Neurobiol Dis
; 124: 340-352, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30528255
8.
Susceptibility of Antibody CDR Residues to Chemical Modifications Can Be Revealed Prior to Antibody Humanization and Aid in the Lead Selection Process.
Mol Pharm
; 15(10): 4529-4537, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30118239
9.
Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics.
J Biol Chem
; 290(50): 29732-41, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491012
10.
Automated Affinity Capture and On-Tip Digestion to Accurately Quantitate in Vivo Deamidation of Therapeutic Antibodies.
Anal Chem
; 88(23): 11521-11526, 2016 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27797494
11.
Molecular basis for negative regulation of the glucagon receptor.
Proc Natl Acad Sci U S A
; 109(36): 14393-8, 2012 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22908259
12.
Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.
J Biol Chem
; 288(50): 36168-78, 2013 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24189067
13.
Corrigendum to "Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS" Neurobiology of Disease 124 (2019) 340-352.
Neurobiol Dis
; 132: 104558, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471201
14.
Structural definition of babesial RAP-1 proteins identifies a novel protein superfamily across Apicomplexa.
Sci Rep
; 13(1): 22330, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38102310
15.
Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease.
Sci Transl Med
; 13(593)2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33980574
16.
Dynamics of heavy chain junctional length biases in antibody repertoires.
Commun Biol
; 3(1): 207, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32358517
17.
Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires.
MAbs
; 12(1): 1722541, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32041466
18.
Immune repertoire mining for rapid affinity optimization of mouse monoclonal antibodies.
MAbs
; 11(4): 735-746, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30900945
19.
Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies.
Commun Biol
; 2: 304, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31428692
20.
The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals.
BMC Mol Biol
; 9: 104, 2008 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19017397