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Nutr Rev ; 80(3): 503-512, 2022 02 10.
Artigo em Inglês | MEDLINE | ID: mdl-33969426

RESUMO

Non-alcoholic fatty liver disease and alcoholic liver disease, the two most prevalent liver diseases worldwide, share a common pathology but have largely been considered disparate diseases. Liver diseases are widely underestimated, but their prevalence is increasing worldwide. The Western diet (high-fat, high-sugar) and binge drinking (rapid consumption of alcohol in a short period of time) are two highly prevalent features of standard life in the United States, and both are linked to the development and progression of liver disease. Yet, few studies have been conducted to elucidate their potential interactions. Data shows binge drinking is on the rise in several age groups, and poor dietary trends continue to be prevalent. This review serves to summarize the sparse findings on the hepatic consequences of the combination of binge drinking and consuming a Western diet, while also drawing conclusions on potential future impacts. The data suggest the potential for a looming liver disease epidemic, indicating that more research on its progression as well as its prevention is needed on this critical topic.


Assuntos
Consumo Excessivo de Bebidas Alcoólicas , Dieta Ocidental , Hepatopatias Alcoólicas , Hepatopatia Gordurosa não Alcoólica , Consumo Excessivo de Bebidas Alcoólicas/complicações , Consumo Excessivo de Bebidas Alcoólicas/patologia , Dieta Hiperlipídica/efeitos adversos , Dieta Ocidental/efeitos adversos , Progressão da Doença , Etanol/efeitos adversos , Humanos , Fígado/patologia , Hepatopatias Alcoólicas/epidemiologia , Hepatopatias Alcoólicas/etiologia , Hepatopatias Alcoólicas/prevenção & controle , Hepatopatia Gordurosa não Alcoólica/epidemiologia , Hepatopatia Gordurosa não Alcoólica/etiologia , Hepatopatia Gordurosa não Alcoólica/prevenção & controle
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