Detalhe da pesquisa
1.
Bactericidal and sterilizing activity of sudapyridine-clofazimine-TB47 combined with linezolid or pyrazinamide in a murine model of tuberculosis.
Antimicrob Agents Chemother
; : e0012424, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38690893
2.
Sterilizing Effects of Novel Regimens Containing TB47, Clofazimine, and Linezolid in a Murine Model of Tuberculosis.
Antimicrob Agents Chemother
; 65(10): e0070621, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34280022
3.
Assessment of Clofazimine and TB47 Combination Activity against Mycobacterium abscessus Using a Bioluminescent Approach.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31843996
4.
Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438933
5.
Indole Propionic Acid Disturbs the Normal Function of Tryptophanyl-tRNA Synthetase in Mycobacterium tuberculosis.
ACS Infect Dis
; 10(4): 1201-1211, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38457660
6.
Distribution of common and rare drug resistance patterns in Mycobacterium tuberculosis clinical isolates revealed by GenoType MTBDRplus and MTBDRsl assay.
J Thorac Dis
; 15(10): 5494-5506, 2023 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37969306
7.
Amino acid 17 in QRDR of Gyrase A plays a key role in fluoroquinolones susceptibility in mycobacteria.
Microbiol Spectr
; 11(6): e0280923, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37831477
8.
Molecular mechanisms of resistance and treatment efficacy of clofazimine and bedaquiline against Mycobacterium tuberculosis.
Front Med (Lausanne)
; 10: 1304857, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38274444
9.
Insight Into Novel Anti-tuberculosis Vaccines by Using Immunoinformatics Approaches.
Front Microbiol
; 13: 866873, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35722321
10.
Uncovering interactions between mycobacterial respiratory complexes to target drug-resistant Mycobacterium tuberculosis.
Front Cell Infect Microbiol
; 12: 980844, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36093195
11.
Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China.
Infect Drug Resist
; 15: 5655-5666, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36193294
12.
Comparative genome analysis reveals high-level drug resistance markers in a clinical isolate of Mycobacterium fortuitum subsp. fortuitum MF GZ001.
Front Cell Infect Microbiol
; 12: 1056007, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36683685
13.
Arabinosyltransferase C Mediates Multiple Drugs Intrinsic Resistance by Altering Cell Envelope Permeability in Mycobacterium abscessus.
Microbiol Spectr
; 10(4): e0276321, 2022 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35946941
14.
Ultra-short-course and intermittent TB47-containing oral regimens produce stable cure against Buruli ulcer in a murine model and prevent the emergence of resistance for Mycobacterium ulcerans.
Acta Pharm Sin B
; 11(3): 738-749, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33777679
15.
A recombinant selective drug-resistant M. bovis BCG enhances the bactericidal activity of a second-line anti-tuberculosis regimen.
Biomed Pharmacother
; 142: 112047, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426260
16.
Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain.
G3 (Bethesda)
; 10(1): 13-22, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31719113
17.
Prevalence and molecular characterization of amikacin resistance among Mycobacterium tuberculosis clinical isolates from southern China.
J Glob Antimicrob Resist
; 22: 290-295, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32142951
18.
Phenotypic and Genotypic Characterization of Streptomycin-Resistant Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China.
Microb Drug Resist
; 26(7): 766-775, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31976809
19.
Rapid, serial, non-invasive quantification of Pseudomonas aeruginosa in live mice with a selectable marker-free autoluminescent strain.
Biosens Bioelectron
; 165: 112396, 2020 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32729517
20.
Design, synthesis, and in vitro biological evaluation of novel benzimidazole tethered allylidenehydrazinylmethylthiazole derivatives as potent inhibitors of Mycobacterium tuberculosis.
Medchemcomm
; 10(1): 49-60, 2019 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30774854