Detalhe da pesquisa
1.
Cathepsin S is a novel target for age-related dry eye.
Exp Eye Res
; 214: 108895, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34910926
2.
Phenylephrine increases tear cathepsin S secretion in healthy murine lacrimal gland acinar cells through an alternative secretory pathway.
Exp Eye Res
; 211: 108760, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34487726
3.
Intralacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjögren's Syndrome.
Biomacromolecules
; 22(3): 1102-1114, 2021 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356170
4.
Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells.
Int J Mol Sci
; 22(4)2021 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33562815
5.
Tear Proteases and Protease Inhibitors: Potential Biomarkers and Disease Drivers in Ocular Surface Disease.
Eye Contact Lens
; 46 Suppl 2: S70-S83, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31369467
6.
Biosynthesized Multivalent Lacritin Peptides Stimulate Exosome Production in Human Corneal Epithelium.
Int J Mol Sci
; 21(17)2020 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32859014
7.
A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye.
Int J Mol Sci
; 21(8)2020 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32326657
8.
Molecular Targeting of Immunosuppressants Using a Bifunctional Elastin-Like Polypeptide.
Bioconjug Chem
; 30(9): 2358-2372, 2019 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31408605
9.
Berunda Polypeptides: Biheaded Rapamycin Carriers for Subcutaneous Treatment of Autoimmune Dry Eye Disease.
Mol Pharm
; 16(7): 3024-3039, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31095909
10.
Longitudinal analysis of tear cathepsin S activity levels in male non-obese diabetic mice suggests its potential as an early stage biomarker of Sjögren's Syndrome.
Biomarkers
; 24(1): 91-102, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30126300
11.
NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis.
Exp Eye Res
; 176: 243-251, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30201519
12.
Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease-Activated Receptor-2, in Human Corneal Epithelial Cells.
Int J Mol Sci
; 19(11)2018 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423938
13.
Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome.
Am J Physiol Cell Physiol
; 310(11): C942-54, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27076615
14.
Polymeric immunoglobulin receptor traffics through two distinct apically targeted pathways in primary lacrimal gland acinar cells.
J Cell Sci
; 126(Pt 12): 2704-17, 2013 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23606742
15.
PP2A: A Novel Target to Prevent Cathepsin S-mediated Damage in Smoking-induced Chronic Obstructive Pulmonary Disease.
Am J Respir Crit Care Med
; 200(1): 6-8, 2019 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30785780
16.
Flipping the Switch on Clathrin-Mediated Endocytosis using Thermally Responsive Protein Microdomains.
Adv Funct Mater
; 24(34): 5340-5347, 2014 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25419208
17.
Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms.
Nanomedicine
; 9(6): 786-94, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23454523
18.
The miRNA Landscape of Lacrimal Glands in a Murine Model of Autoimmune Dacryoadenitis.
Invest Ophthalmol Vis Sci
; 64(4): 1, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37010857
19.
Tear miRNAs Identified in a Murine Model of Sjögren's Syndrome as Potential Diagnostic Biomarkers and Indicators of Disease Mechanism.
Front Immunol
; 13: 833254, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35309364
20.
Supra-lacrimal protein-based carriers for cyclosporine A reduce Th17-mediated autoimmunity in murine model of Sjögren's syndrome.
Biomaterials
; 283: 121441, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35306230