Detalhe da pesquisa
1.
Increasing Linker Chain Length and Intestinal Stability Enhances Lymphatic Transport and Lymph Node Exposure of Triglyceride Mimetic Prodrugs of a Model Immunomodulator Mycophenolic Acid.
Mol Pharm
; 20(5): 2675-2685, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996486
2.
Classifying social determinants of health from unstructured electronic health records using deep learning-based natural language processing.
J Biomed Inform
; 127: 103984, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007754
3.
Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles.
Pharm Res
; 38(9): 1497-1518, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34463935
4.
Lymphatic Uptake of Liposomes after Intraperitoneal Administration Primarily Occurs via the Diaphragmatic Lymphatics and is Dependent on Liposome Surface Properties.
Mol Pharm
; 16(12): 4987-4999, 2019 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625752
5.
Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations.
Mol Pharm
; 15(12): 5678-5696, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30376336
6.
Computational Models of the Gastrointestinal Environment. 2. Phase Behavior and Drug Solubilization Capacity of a Type I Lipid-Based Drug Formulation after Digestion.
Mol Pharm
; 14(3): 580-592, 2017 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27936778
7.
Lymphatic Transport and Lymphocyte Targeting of a Triglyceride Mimetic Prodrug Is Enhanced in a Large Animal Model: Studies in Greyhound Dogs.
Mol Pharm
; 13(10): 3351-3361, 2016 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27608166
8.
Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.
Angew Chem Int Ed Engl
; 55(44): 13700-13705, 2016 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27482655
9.
Profiling the role of deacylation-reacylation in the lymphatic transport of a triglyceride-mimetic prodrug.
Pharm Res
; 32(5): 1830-44, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25446770
10.
On the popularity of the USB flash drive-shaped electronic cigarette Juul.
Tob Control
; 28(1): 110-112, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29654121
11.
Lymphatic Uptake of a Highly Lipophilic Protease Inhibitor Prodrug from a Lipid-Based Formulation is Limited by Instability in the Intestine.
J Pharm Sci
; 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38582284
12.
Extracting social determinants of health events with transformer-based multitask, multilabel named entity recognition.
J Am Med Inform Assoc
; 30(8): 1379-1388, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37002953
13.
Antibody drug conjugate: the "biological missile" for targeted cancer therapy.
Signal Transduct Target Ther
; 7(1): 93, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35318309
14.
Corrigendum: Triglyceride-mimetic prodrugs of buprenorphine enhance oral bioavailability via promotion of lymphatic transport.
Front Pharmacol
; 13: 1014363, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36133812
15.
Triglyceride-Mimetic Prodrugs of Buprenorphine Enhance Oral Bioavailability via Promotion of Lymphatic Transport.
Front Pharmacol
; 13: 879660, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35496278
16.
The Impact of Conjugation Position and Linker Chemistry on the Lymphatic Transport of a Series of Glyceride and Phospholipid Mimetic Prodrugs.
J Pharm Sci
; 110(1): 489-499, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33069711
17.
Intestinal delivery in a long-chain fatty acid formulation enables lymphatic transport and systemic exposure of orlistat.
Int J Pharm
; 596: 120247, 2021 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33486039
18.
Analytical validation of GMEX rapid point-of-care CYP2C19 genotyping system for the CHANCE-2 trial.
Stroke Vasc Neurol
; 6(2): 274-279, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33952669
19.
Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice.
J Control Release
; 332: 636-651, 2021 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33609620
20.
Intestinal Lymph Flow, and Lipid and Drug Transport Scale Allometrically From Pre-clinical Species to Humans.
Front Physiol
; 11: 458, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32670074