RESUMO
A case of Stevens-Johnson syndrome following treatment with sodium valproate is presented here. A 20-year-old male was put on sodium valproate monotherapy for the migraine, with generalized epilepsy. He developed vesicles and bullae in the oral and nasal mucosa with conjunctivitis, after 10 days of treatment. The lesions resolved after treating with systemic steroids. This case has been presented because Stevens-Johnson syndrome with sodium valproate monotherapy has been very rarely reported.
RESUMO
Pseudoepitheliomatous, keratotic, and micaceous balanitis is an extremely rare condition occurring over the glans in elderly characterized by silvery white plaque with mica-like crust, which can undergo malignant transformation. Herein we present a case of pseudoepitheliomatous, keratotic, and micaceous balanitis occurring in an adult male presenting as a cutaneous horn.
Assuntos
Balanite (Inflamação)/patologia , Ceratose/patologia , Lesões Pré-Cancerosas/patologia , Adulto , Biópsia , Diagnóstico Diferencial , Progressão da Doença , Humanos , Masculino , Pênis/patologiaRESUMO
Histoplasmosis, also called as Darling's disease, is caused by the dimorphic fungus, Histoplasma capsulatum. In India, several cases of histoplasmosis have been reported since 1954, but in only a few cases could the diagnosis be confirmed by fungal culture. Disseminated histoplasmosis in adults is often associated with immunosuppression, as in human immunodeficiency virus (HIV) infection. Oral lesions are seen in 30-50% of the patients. Here, we are reporting two histoplasmosis cases, one with disseminated histoplasmosis with extensive skin and oral lesions in a known HIV-positive patient and the second case presenting with ulcer of the tongue, found to be HIV positive on investigation. It is important to consider histoplasmosis as one of the differential diagnosis of oral lesions in HIV-infected individuals.
Assuntos
Infecções por HIV/complicações , Infecções por HIV/diagnóstico , Histoplasmose/complicações , Histoplasmose/diagnóstico , Adulto , Antirretrovirais/uso terapêutico , Feminino , Infecções por HIV/tratamento farmacológico , Histoplasmose/tratamento farmacológico , Humanos , MasculinoAssuntos
Hanseníase/complicações , Hanseníase/tratamento farmacológico , Doenças do Sistema Nervoso Periférico/tratamento farmacológico , Doenças do Sistema Nervoso Periférico/microbiologia , Esteroides/administração & dosagem , Relação Dose-Resposta a Droga , Humanos , Pacientes Ambulatoriais , Resultado do TratamentoRESUMO
Porokeratosis of Mibelli is a genetic disease transmitted as an autosomal dominant trait. The giant type of porokeratosis is a relatively rare entity and is associated with an increased risk of malignancy. The aim of this article is to present this rare case of giant porokeratosis associated with squamous cell carcinoma.