Detalhe da pesquisa
1.
Targeting insulin-like growth factor-1 receptor (IGF1R) for brain delivery of biologics.
FASEB J
; 36(3): e22208, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192204
2.
TNF receptor-associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation.
J Biol Chem
; 295(12): 3808-3825, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029478
3.
Serum albumin-binding VH Hs with variable pH sensitivities enable tailored half-life extension of biologics.
FASEB J
; 34(6): 8155-8171, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342547
4.
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system.
Nat Immunol
; 9(2): 137-45, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18157132
5.
Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity.
J Neurochem
; 146(6): 735-752, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29877588
6.
Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26.
Mol Pharm
; 15(4): 1420-1431, 2018 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29485883
7.
Brain penetration, target engagement, and disposition of the blood-brain barrier-crossing bispecific antibody antagonist of metabotropic glutamate receptor type 1.
FASEB J
; 30(5): 1927-40, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26839377
8.
A novel platform for engineering blood-brain barrier-crossing bispecific biologics.
FASEB J
; 28(11): 4764-78, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25070367
9.
The proteome of the blood-brain barrier in rat and mouse: highly specific identification of proteins on the luminal surface of brain microvessels by in vivo glycocapture.
Fluids Barriers CNS
; 21(1): 23, 2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38433215
10.
Multiplexed evaluation of serum and CSF pharmacokinetics of brain-targeting single-domain antibodies using a NanoLC-SRM-ILIS method.
Mol Pharm
; 10(5): 1542-56, 2013 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23150993
11.
Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat.
Pharmaceutics
; 15(5)2023 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242805
12.
Proteome Profiling of Brain Vessels in a Mouse Model of Cerebrovascular Pathology.
Biology (Basel)
; 12(12)2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38132326
13.
Mouse embryonic stem cell-derived blood-brain barrier model: applicability to studying antibody triggered receptor mediated transcytosis.
Fluids Barriers CNS
; 20(1): 36, 2023 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37237379
14.
Assessment of brain-derived extracellular vesicle enrichment for blood biomarker analysis in age-related neurodegenerative diseases: An international overview.
bioRxiv
; 2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37873207
15.
Immunoassay for Quantitative Detection of Antibody Transcytosis Across the Blood-Brain Barrier In Vitro.
Methods Mol Biol
; 2549: 345-357, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35218529
16.
Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity.
Brain Commun
; 4(6): fcac309, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36523269
17.
Brain Delivery of IGF1R5, a Single-Domain Antibody Targeting Insulin-like Growth Factor-1 Receptor.
Pharmaceutics
; 14(7)2022 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890347
18.
Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier.
Cell Rep Methods
; 2(11): 100338, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36452865
19.
Proteome of the Luminal Surface of the Blood-Brain Barrier.
Proteomes
; 9(4)2021 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34842825
20.
Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures.
Viruses
; 13(5)2021 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33946875