Detalhe da pesquisa
1.
Correction: The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3'-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis.
PLoS Genet
; 20(1): e1011124, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38236804
2.
Human DNA polymerase η promotes RNA-templated error-free repair of DNA double-strand breaks.
J Biol Chem
; 299(3): 102991, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36758800
3.
Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin.
Nucleic Acids Res
; 49(1): 221-243, 2021 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33300026
4.
Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription.
Proc Natl Acad Sci U S A
; 117(36): 22183-22192, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32826329
5.
Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis.
Proc Natl Acad Sci U S A
; 117(14): 8154-8165, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32205441
6.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Alzheimers Dement
; 19(4): 1245-1259, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993441
7.
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
Proc Natl Acad Sci U S A
; 116(10): 4696-4705, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770445
8.
DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders.
Int J Mol Sci
; 23(9)2022 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563044
9.
Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Hum Mol Genet
; 28(15): 2459-2476, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31067307
10.
Cannabinoid exposure during pregnancy and its impact on immune function.
Cell Mol Life Sci
; 76(4): 729-743, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-30374520
11.
Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.
Nucleic Acids Res
; 45(5): 2585-2599, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27994036
12.
Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A.
Nucleic Acids Res
; 45(2): 739-748, 2017 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27794043
13.
Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis.
Int J Mol Sci
; 20(22)2019 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31703296
14.
The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.
PLoS Genet
; 11(1): e1004749, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25633985
15.
Oxidized Guanine Base Lesions Function in 8-Oxoguanine DNA Glycosylase-1-mediated Epigenetic Regulation of Nuclear Factor κB-driven Gene Expression.
J Biol Chem
; 291(49): 25553-25566, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27756845
16.
The C-terminal Domain (CTD) of Human DNA Glycosylase NEIL1 Is Required for Forming BERosome Repair Complex with DNA Replication Proteins at the Replicating Genome: DOMINANT NEGATIVE FUNCTION OF THE CTD.
J Biol Chem
; 290(34): 20919-20933, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26134572
17.
Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Hum Mol Genet
; 28(18): 3161-3162, 2019 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504503
18.
New paradigms in the repair of oxidative damage in human genome: mechanisms ensuring repair of mutagenic base lesions during replication and involvement of accessory proteins.
Cell Mol Life Sci
; 72(9): 1679-98, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25575562
19.
Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins.
Proc Natl Acad Sci U S A
; 110(33): E3090-9, 2013 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23898192
20.
The role of 8-oxoguanine DNA glycosylase-1 in inflammation.
Int J Mol Sci
; 15(9): 16975-97, 2014 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25250913