Detalhe da pesquisa
1.
Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell
; 148(4): 727-38, 2012 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22341445
2.
A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit ß5i.
EMBO J
; 35(23): 2602-2613, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27789522
3.
Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome.
Chembiochem
; 18(6): 523-526, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28098422
4.
Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J Am Chem Soc
; 137(24): 7835-42, 2015 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26020686
5.
Structure-Based Design of Inhibitors Selective for Human Proteasome ß2c or ß2i Subunits.
J Med Chem
; 62(3): 1626-1642, 2019 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30657666
6.
Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
Sci Rep
; 8(1): 5975, 2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29654304
7.
A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun
; 7: 10900, 2016 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26964885
8.
Bortezomib-resistant mutant proteasomes: structural and biochemical evaluation with carfilzomib and ONX 0914.
Structure
; 23(2): 407-17, 2015 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25599643
9.
Interactions of the natural product kendomycin and the 20S proteasome.
J Mol Biol
; 426(18): 3108-3117, 2014 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25038530