RESUMO
BACKGROUND: To explore whether Tension-free Vaginal Tape offers a solution for women with cystic fibrosis who suffer from severe stress incontinence. METHODS: Four adults with cystic fibrosis were formally assessed by gynaecological and urological specialists, prior to hospital admission for surgery. RESULTS: The procedure was tolerated well by all patients. In three, leakage ceased completely. The fourth patient experienced considerable improvement in symptoms. CONCLUSIONS: Tension-free Vaginal Tape is a safe, effective and worthwhile solution for stress incontinence in females with cystic fibrosis.
Assuntos
Fibrose Cística/complicações , Slings Suburetrais , Incontinência Urinária por Estresse/cirurgia , Adulto , Fibrose Cística/cirurgia , Feminino , Humanos , Pessoa de Meia-Idade , Resultado do Tratamento , Incontinência Urinária por Estresse/etiologiaRESUMO
We evaluated early social risk assessment as a predictor of cognitive development in high-risk infants. A social worker assessed social risk in 122 infants before discharge from a neonatal intensive care unit. Infants were evaluated at ages 12 and 36 months adjusted for prematurity. We found no difference in 12-month cognitive development among medical, neurologic, or social risk groups. However, from 12 to 36 months there was a significant decline in mean developmental quotient in the groups with social risk alone, neurologic and social risk, and medical and social risk, but not in the groups with medical or neurologic risks without social risk. Social risk assessment correctly predicted 36-month cognitive outcome in 71% of infants who had normal findings at 12 months. We conclude that neonatal social risk assessment can help identify infants at highest risk for cognitive retardation and is particularly important for infants who have medical or neurologic problems.
Assuntos
Desenvolvimento Infantil , Transtornos Cognitivos/etiologia , Insuficiência de Crescimento , Distribuição de Qui-Quadrado , Desenvolvimento Infantil/fisiologia , Pré-Escolar , Transtornos Cognitivos/diagnóstico , Transtornos Cognitivos/epidemiologia , Transtornos Cognitivos/fisiopatologia , Insuficiência de Crescimento/diagnóstico , Insuficiência de Crescimento/epidemiologia , Insuficiência de Crescimento/fisiopatologia , Feminino , Seguimentos , Humanos , Lactente , Recém-Nascido , Unidades de Terapia Intensiva Neonatal , Masculino , North Carolina , Medição de Risco , Serviço Social , Fatores SocioeconômicosAssuntos
Moléculas de Adesão Celular/genética , Polimorfismo de Fragmento de Restrição , Suínos/genética , Animais , Cruzamento , Adesão Celular/genética , DNA/análise , Desoxirribonucleases de Sítio Específico do Tipo II , Frequência do Gene , Genes de Imunoglobulinas , Molécula 1 de Adesão de Célula VascularRESUMO
This paper reviews current literature on feeding and swallowing of the premature and high-risk infant. If addresses issues of maturation and organization that affect feeding abilities. Evaluation issues including instrumental evaluations (e.g., cervical auscultation, modified barium swallow studies) are discussed. Finally, common problems seen in this population are described along with the wide range of management strategies to consider. Whenever intervening with this fragile population a team approach must be used; the individual needs and behavioral cues of the infant must be read, respected, and responded to, while ensuring that families play an integral part of the process.
Assuntos
Transtornos de Deglutição/diagnóstico , Transtornos de Deglutição/reabilitação , Unidades de Terapia Intensiva Pediátrica , Transtornos de Deglutição/complicações , Refluxo Gastroesofágico/diagnóstico , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Transtornos Respiratórios/complicações , Comportamento de SucçãoRESUMO
Vertical polyacrylamide gel electrophoresis was used to separate enzyme proteins at 73 putative loci in natural house fly populations sampled in central Iowa. Thirty-nine of the loci were polymorphic (53%). The mean effective number of alleles per polymorphic locus was 1.93 and 1.47 alleles among 68 scored loci. Observed and expected heterozygosities at 34 house fly loci were 0.1628 and 0.1834, respectively. No statistically significant differentiation was detected among nine central Iowa fly populations in 1989 or among nine Iowa and three Minnesota populations in 1990.
Assuntos
Variação Genética , Moscas Domésticas/genética , Animais , Eletroforese em Gel de Poliacrilamida , Enzimas/genética , Heterozigoto , Moscas Domésticas/enzimologia , Polimorfismo GenéticoRESUMO
PURPOSE: The purpose of this study was to describe the range and frequency of behaviors in neonates 24-30 weeks postconceptional age (PCA) using the Newborn Individualized Developmental Care Assessment Program (NIDCAP). DESIGN: A prospective design with convenience sampling was used. SAMPLE: Starting 24-72 hours postnatally and continuing through 30 weeks PCA, 8,144 two-minute observations of 85 NIDCAP behaviors were collected and analyzed from 42 neonates born at 24-29 weeks gestation. MAIN OUTCOME VARIABLE: The main outcome variables were the frequencies of the 85 neonatal behaviors measured by the NIDCAP. Frequencies were organized first by subsystem (autonomic, motor, or state) and were categorized further based on week of PCA. Comparisons of behavioral frequencies by number of weeks PCA were completed using correlation and regression analyses. RESULTS: The most frequently observed behaviors were irregular respirations, pink color, postured flexion of the extremities, immature light sleep, and drowsiness. Least frequently observed behaviors consisted of burps, bowel movement, grunting, smooth motor movements, cooing, and speech movement. Regression analysis illustrated that the pattern of behavior was significantly similar week to week.