Detalhe da pesquisa
1.
Collaborative SAR Modeling and Prospective In Vitro Validation of Oxidative Stress Activation in Human HepG2 Cells.
J Chem Inf Model
; 63(17): 5433-5445, 2023 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37616385
2.
High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.
Arch Toxicol
; 93(10): 2895-2911, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31552476
3.
Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury.
Arch Toxicol
; 92(5): 1797-1814, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29502165
4.
Comprehensive Landscape of Nrf2 and p53 Pathway Activation Dynamics by Oxidative Stress and DNA Damage.
Chem Res Toxicol
; 30(4): 923-933, 2017 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27982581
5.
High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities.
Arch Toxicol
; 91(3): 1367-1383, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27358234
6.
Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment.
Chem Res Toxicol
; 27(3): 338-55, 2014 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24450961
7.
DAYSLEEPER: a nuclear and vesicular-localized protein that is expressed in proliferating tissues.
BMC Plant Biol
; 13: 211, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24330683
8.
Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses.
Toxicol In Vitro
; 84: 105419, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35724838
9.
Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure.
Sci Rep
; 12(1): 7336, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35513409
10.
Mining a human transcriptome database for chemical modulators of NRF2.
PLoS One
; 15(9): e0239367, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32986742
11.
Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells.
Front Pharmacol
; 9: 388, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29720942