Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways.

Okubo, Yusuke; Ohtake, Fumiaki; Igarashi, Katsuhide; Yasuhiko, Yukuto; Hirabayashi, Yoko; Saga, Yumiko; Kanno, Jun.

Development ; 148(19)2021 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-34519339

2.

Macrophage depletion using clodronate liposomes reveals latent dysfunction of the hematopoietic microenvironment associated with persistently imbalanced M1/M2 macrophage polarization in a mouse model of hemophagocytic lymphohistiocytosis.

Koike, Takashi; Miura, Katsuhiro; Hatta, Yoshihiro; Nakamura, Hideki; Hirabayashi, Yoko; Yuda, Miyuki; Harada, Tomonori; Hirai, Shuichi; Tsuboi, Isao; Aizawa, Shin.

Ann Hematol ; 102(12): 3311-3323, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37656190

3.

International regulatory uses of acute systemic toxicity data and integration of new approach methodologies.

Strickland, Judy; Haugabrooks, Esther; Allen, David G; Balottin, Luciene B; Hirabayashi, Yoko; Kleinstreuer, Nicole C; Kojima, Hajime; Nishizawa, Claudio; Prieto, Pilar; Ratzlaff, Deborah E; Jeong, Jayoung; Lee, JinHee; Yang, Ying; Lin, Pinpin; Sullivan, Kristie; Casey, Warren.

Crit Rev Toxicol ; 53(7): 385-411, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37646804

4.

Imbalanced M1 and M2 Macrophage Polarization in Bone Marrow Provokes Impairment of the Hematopoietic Microenvironment in a Mouse Model of Hemophagocytic Lymphohistiocytosis.

Yuda, Miyuki; Aizawa, Shin; Tsuboi, Isao; Hirabayashi, Yoko; Harada, Tomonori; Hino, Hirotsugu; Hirai, Shuichi.

Biol Pharm Bull ; 45(11): 1602-1608, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36328495

5.

Dynamics of hematopoiesis is disrupted by impaired hematopoietic microenvironment in a mouse model of hemophagocytic lymphohistiocytosis.

Tsuboi, Isao; Harada, Tomonori; Hirabayashi, Yoko; Aizawa, Shin.

Ann Hematol ; 99(7): 1515-1523, 2020 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-32506245

6.

Senescence-accelerated mice (SAMP1/TA-1) treated repeatedly with lipopolysaccharide develop a condition that resembles hemophagocytic lymphohistiocytosis.

Tsuboi, Isao; Harada, Tomonori; Hirabayashi, Yoko; Aizawa, Shin.

Haematologica ; 104(10): 1995-2005, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-30819910

7.

Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes.

Oka, Shin-Ichi; Hirata, Tsuyoshi; Suzuki, Wataru; Naito, Daichi; Chen, Yanbin; Chin, Adave; Yaginuma, Hiroaki; Saito, Toshiro; Nagarajan, Narayani; Zhai, Peiyong; Bhat, Santosh; Schesing, Kevin; Shao, Dan; Hirabayashi, Yoko; Yodoi, Junji; Sciarretta, Sebastiano; Sadoshima, Junichi.

J Biol Chem ; 292(46): 18988-19000, 2017 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-28939765

8.

Differential Regulation of Lympho-Myelopoiesis by Stromal Cells in the Early and Late Phases in BALB/c Mice Repeatedly Exposed to Lipopolysaccharide.

Tsuboi, Isao; Harada, Tomonori; Hirabayashi, Yoko; Kanno, Jun; Aizawa, Shin.

Biol Pharm Bull ; 39(12): 1939-1947, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-27904036

9.

Experimentally induced, synergistic late effects of a single dose of radiation and aging: significance in LKS fraction as compared with mature blood cells.

Hirabayashi, Yoko; Tsuboi, Isao; Nakachi, Kei; Kusunoki, Yoichiro; Inoue, Tohru.

J Appl Toxicol ; 35(3): 230-40, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25413632

10.

[New Approach Method for drug discovery and development aimed at regulatory acceptance].

Kojima, Hajime; Hirabayashi, Yoko.

Nihon Yakurigaku Zasshi ; 158(3): 269-272, 2023.

Artigo em Japonês | MEDLINE | ID: mdl-37121711

11.

Mast cell development and biostresses: different stromal responses in bone marrow and spleen after treatment of myeloablater, 5-fluorouracil, and inflammatory stressor, lipopolysaccharide.

Hokari, Takeo; Tsuboi, Isao; Harada, Tomonori; Oshima, Hideki; Hirabayashi, Yoko; Kanno, Jun; Inoue, Tohru; Aizawa, Shin.

Biol Pharm Bull ; 34(10): 1533-41, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21963492

12.

The low-dose issue and stochastic responses to endocrine disruptors.

Hirabayashi, Yoko; Inoue, Tohru.

J Appl Toxicol ; 31(1): 84-8, 2011 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-20683855

13.

Age-related exacerbation of hematopoietic organ damage induced by systemic hyper-inflammation in senescence-accelerated mice.

Harada, Tomonori; Tsuboi, Isao; Hino, Hirotsugu; Yuda, Miyuki; Hirabayashi, Yoko; Hirai, Shuichi; Aizawa, Shin.

Sci Rep ; 11(1): 23250, 2021 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-34853370

14.

Visualizing the spatial localization of ciclesonide and its metabolites in rat lungs after inhalation of 1-µm aerosol of ciclesonide by desorption electrospray ionization-time of flight mass spectrometry imaging.

Yamamoto, Eiichi; Taquahashi, Yuhji; Kuwagata, Makiko; Saito, Hirokatsu; Matsushita, Kohei; Toyoda, Takeshi; Sato, Futoshi; Kitajima, Satoshi; Ogawa, Kumiko; Izutsu, Ken-Ichi; Saito, Yoshiro; Hirabayashi, Yoko; Iimura, Yasuo; Honma, Masamitsu; Okuda, Haruhiro; Goda, Yukihiro.

Int J Pharm ; 595: 120241, 2021 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-33484917

15.

Considerations of the Japanese Research Working Group for the ICH S6 & Related Issues Regarding Nonclinical Safety Assessments of Oligonucleotide Therapeutics: Comparison with Those of Biopharmaceuticals.

Hirabayashi, Yoko; Maki, Kazushige; Kinoshita, Kiyoshi; Nakazawa, Takahiro; Obika, Satoshi; Naota, Misaki; Watanabe, Kazuto; Suzuki, Mutsumi; Arato, Teruyo; Fujisaka, Aki; Fueki, Osamu; Ito, Kosuke; Onodera, Hiroshi.

Nucleic Acid Ther ; 31(2): 114-125, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33470890

16.

Memorial address to Dr Tohru Inoue.

Hirabayashi, Yoko.

J Appl Toxicol ; 35(3): 229, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25626849

17.

Novel hepatotoxicity biomarkers of extracellular vesicle (EV)-associated miRNAs induced by CCl4.

Ono, Ryuichi; Yoshioka, Yusuke; Furukawa, Yusuke; Naruse, Mie; Kuwagata, Makiko; Ochiya, Takahiro; Kitajima, Satoshi; Hirabayashi, Yoko.

Toxicol Rep ; 7: 685-692, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32528856

18.

Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart.

Oka, Shin-Ichi; Chin, Adave; Park, Ji Yeon; Ikeda, Shohei; Mizushima, Wataru; Ralda, Guersom; Zhai, Peiyong; Tong, Mingming; Byun, Jaemin; Tang, Fan; Einaga, Yudai; Huang, Chun-Yang; Kashihara, Toshihide; Zhao, Mengyuan; Nah, Jihoon; Tian, Bin; Hirabayashi, Yoko; Yodoi, Junji; Sadoshima, Junichi.

Cardiovasc Res ; 116(10): 1742-1755, 2020 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-31584633

19.

Benzene activates caspase-4 and -12 at the transcription level, without an association with apoptosis, in mouse bone marrow cells lacking the p53 gene.

Yi, Jung-Yeon; Hirabayashi, Yoko; Choi, Yang-Kyu; Kodama, Yukio; Kanno, Jun; Han, Jeong-Hee; Inoue, Tohru; Yoon, Byung-Il.

Arch Toxicol ; 83(8): 795-803, 2009 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-19326098

20.

[A case of chemo-radiation therapy with high degree of efficacy for esophageal cancer with liver metastasis].

Kubota, Hisako; Matsumoto, Hideo; Saito, Ai; Kaida, Yuko; Murakami, Haruaki; Higashida, Masaharu; Hirabayashi, Yoko; Oka, Yasuo; Okumura, Hideo; Uragami, Atsushi; Yamashita, Kazuki; Hirai, Toshihiro; Yoden, Eisaku; Hiratsuka, Junichi.

Gan To Kagaku Ryoho ; 36(12): 2045-8, 2009 Nov.

Artigo em Japonês | MEDLINE | ID: mdl-20037318

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