Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

HIV and FIV glycoproteins increase cellular tau pathology via cGMP-dependent kinase II activation.

Sathler, Matheus F; Doolittle, Michael J; Cockrell, James A; Nadalin, India R; Hofmann, Franz; VandeWoude, Sue; Kim, Seonil.

J Cell Sci ; 135(12)2022 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-35638570

2.

L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.

Hofmann, Franz; Flockerzi, Veit; Kahl, Sabine; Wegener, Jörg W.

Physiol Rev ; 94(1): 303-26, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24382889

3.

HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model.

Sztukowski, Keira; Nip, Kaila; Ostwald, Paige N; Sathler, Matheus F; Sun, Julianna L; Shou, Jiayi; Jorgensen, Emily T; Brown, Travis E; Elder, John H; Miller, Craig; Hofmann, Franz; VandeWoude, Sue; Kim, Seonil.

PLoS Biol ; 16(7): e2005315, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-30052626

4.

Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the ß2 adrenergic receptor.

Patriarchi, Tommaso; Qian, Hai; Di Biase, Valentina; Malik, Zulfiquar A; Chowdhury, Dhrubajyoti; Price, Jennifer L; Hammes, Erik A; Buonarati, Olivia R; Westenbroek, Ruth E; Catterall, William A; Hofmann, Franz; Xiang, Yang K; Murphy, Geoffrey G; Chen, Chao-Ye; Navedo, Manuel F; Hell, Johannes W.

EMBO J ; 35(12): 1330-45, 2016 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-27103070

5.

The cGMP system: components and function.

Hofmann, Franz.

Biol Chem ; 401(4): 447-469, 2020 03 26.

Artigo em Inglês | MEDLINE | ID: mdl-31747372

6.

A concise discussion of the regulatory role of cGMP kinase I in cardiac physiology and pathology.

Hofmann, Franz.

Basic Res Cardiol ; 113(4): 31, 2018 06 22.

Artigo em Inglês | MEDLINE | ID: mdl-29934662

7.

Protein kinases G are essential downstream mediators of the antifibrotic effects of sGC stimulators.

Matei, Alexandru-Emil; Beyer, Christian; Györfi, Andrea-Hermina; Soare, Alina; Chen, Chih-Wei; Dees, Clara; Bergmann, Christina; Ramming, Andreas; Friebe, Andreas; Hofmann, Franz; Distler, Oliver; Schett, Georg; Distler, Jörg H W.

Ann Rheum Dis ; 77(3): 459, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29311148

8.

cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium.

Wang, Rui; Islam, Bianca N; Bridges, Allison; Sharman, Sarah K; Hu, Muhan; Hou, Yali; Somanath, Payaningal R; Venable, Laine; Singh, Nagendra; Kim, Sangmi; Sridhar, Subbaramiah; Hofmann, Franz; Browning, Darren D.

Am J Pathol ; 187(2): 377-389, 2017 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-27998725

9.

Network compensation of cyclic GMP-dependent protein kinase II knockout in the hippocampus by Ca2+-permeable AMPA receptors.

Kim, Seonil; Titcombe, Roseann F; Zhang, Hong; Khatri, Latika; Girma, Hiwot K; Hofmann, Franz; Arancio, Ottavio; Ziff, Edward B.

Proc Natl Acad Sci U S A ; 112(10): 3122-7, 2015 Mar 10.

Artigo em Inglês | MEDLINE | ID: mdl-25713349

10.

Beta-adrenergic regulation of the heart expressing the Ser1700A/Thr1704A mutated Cav1.2 channel.

Poomvanicha, Montatip; Matthes, Jan; Domes, Katrin; Patrucco, Enrico; Angermeier, Elisabeth; Laugwitz, Karl-Ludwig; Schneider, Toni; Hofmann, Franz.

J Mol Cell Cardiol ; 111: 10-16, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28778765

11.

Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.

Patrucco, Enrico; Domes, Katrin; Sbroggió, Mauro; Blaich, Anne; Schlossmann, Jens; Desch, Matthias; Rybalkin, Sergei D; Beavo, Joseph A; Lukowski, Robert; Hofmann, Franz.

Proc Natl Acad Sci U S A ; 111(35): 12925-9, 2014 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-25139994

12.

Altered Synaptic Membrane Retrieval after Strong Stimulation of Cerebellar Granule Neurons in Cyclic GMP-Dependent Protein Kinase II (cGKII) Knockout Mice.

Collado-Alsina, Andrea; Hofmann, Franz; Sánchez-Prieto, José; Torres, Magdalena.

Int J Mol Sci ; 18(11)2017 Oct 30.

Artigo em Inglês | MEDLINE | ID: mdl-29084181

13.

Brain region-specific effects of cGMP-dependent kinase II knockout on AMPA receptor trafficking and animal behavior.

Kim, Seonil; Pick, Joseph E; Abera, Sinedu; Khatri, Latika; Ferreira, Danielle D P; Sathler, Matheus F; Morison, Sage L; Hofmann, Franz; Ziff, Edward B.

Learn Mem ; 23(8): 435-41, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-27421896

14.

L-type Calcium Channel Cav1.2 Is Required for Maintenance of Auditory Brainstem Nuclei.

Ebbers, Lena; Satheesh, Somisetty V; Janz, Katrin; Rüttiger, Lukas; Blosa, Maren; Hofmann, Franz; Morawski, Markus; Griesemer, Désirée; Knipper, Marlies; Friauf, Eckhard; Nothwang, Hans Gerd.

J Biol Chem ; 290(39): 23692-710, 2015 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-26242732

15.

CaV1.2 and CaV1.3 channel hyperactivation in mouse islet ß cells exposed to type 1 diabetic serum.

Yang, Guang; Shi, Yue; Yu, Jia; Li, Yuxin; Yu, Lina; Welling, Andrea; Hofmann, Franz; Striessnig, Jörg; Juntti-Berggren, Lisa; Berggren, Per-Olof; Yang, Shao-Nian.

Cell Mol Life Sci ; 72(6): 1197-207, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25292336

16.

Murine cardiac growth, TRPC channels, and cGMP kinase I.

Domes, Katrin; Patrucco, Enrico; Loga, Florian; Dietrich, Alexander; Birnbaumer, Lutz; Wegener, Jörg W; Hofmann, Franz.

Pflugers Arch ; 467(10): 2229-34, 2015 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25547873

17.

Phospholipase D1 is involved in α1-adrenergic contraction of murine vascular smooth muscle.

Wegener, Jörg W; Loga, Florian; Stegner, David; Nieswandt, Bernhard; Hofmann, Franz.

FASEB J ; 28(3): 1044-8, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24253251

18.

Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.

Luo, Ceng; Gangadharan, Vijayan; Bali, Kiran Kumar; Xie, Rou-Gang; Agarwal, Nitin; Kurejova, Martina; Tappe-Theodor, Anke; Tegeder, Irmgard; Feil, Susanne; Lewin, Gary; Polgar, Erika; Todd, Andrew J; Schlossmann, Jens; Hofmann, Franz; Liu, Da-Lu; Hu, San-Jue; Feil, Robert; Kuner, Thomas; Kuner, Rohini.

PLoS Biol ; 10(3): e1001283, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-22427743

19.

Angiotensin II dose-dependently stimulates human renal proximal tubule transport by the nitric oxide/guanosine 3',5'-cyclic monophosphate pathway.

Shirai, Ayumi; Yamazaki, Osamu; Horita, Shoko; Nakamura, Motonobu; Satoh, Nobuhiko; Yamada, Hideomi; Suzuki, Masashi; Kudo, Akihiko; Kawakami, Hayato; Hofmann, Franz; Nishiyama, Akira; Kume, Haruki; Enomoto, Yutaka; Homma, Yukio; Seki, George.

J Am Soc Nephrol ; 25(7): 1523-32, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24511122

20.

Na+ current properties in islet α- and ß-cells reflect cell-specific Scn3a and Scn9a expression.

Zhang, Quan; Chibalina, Margarita V; Bengtsson, Martin; Groschner, Lukas N; Ramracheya, Reshma; Rorsman, Nils J G; Leiss, Veronika; Nassar, Mohammed A; Welling, Andrea; Gribble, Fiona M; Reimann, Frank; Hofmann, Franz; Wood, John N; Ashcroft, Frances M; Rorsman, Patrik.

J Physiol ; 592(21): 4677-96, 2014 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-25172946

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