Detalhe da pesquisa
1.
Preclinical development of a vaccine-based immunotherapy regimen (VBIR) that induces potent and durable T cell responses to tumor-associated self-antigens.
Cancer Immunol Immunother
; 72(2): 287-300, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35829790
2.
Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment.
FASEB J
; 26(12): 5172-81, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22898924
3.
Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.
J Cell Sci
; 123(Pt 19): 3336-46, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20826454
4.
The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property?
Mol Pharmacol
; 75(3): 490-501, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19064629
5.
CD44 modulates Smad1 activation in the BMP-7 signaling pathway.
J Cell Biol
; 166(7): 1081-91, 2004 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-15452148
6.
Turning the corner on therapeutic cancer vaccines.
NPJ Vaccines
; 4: 7, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30774998
7.
Apoptotic regulation by the Crk adapter protein mediated by interactions with Wee1 and Crm1/exportin.
Mol Cell Biol
; 22(5): 1412-23, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11839808
8.
5T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma.
Clin Cancer Res
; 23(10): 2516-2527, 2017 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27780858
9.
Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody-Drug Conjugate Targeting 5T4.
Mol Cancer Ther
; 16(8): 1576-1587, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28522587
10.
A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response.
Mol Cancer Ther
; 15(4): 689-701, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26880266
11.
IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence.
Neoplasia
; 18(5): 273-281, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27237319
12.
A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.
Cancer Res
; 76(2): 480-90, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26744529
13.
Therapeutic Efficacy of Cancer Stem Cell Vaccines in the Adjuvant Setting.
Cancer Res
; 76(16): 4661-72, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27325649
14.
Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics.
J Control Release
; 236: 100-16, 2016 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27327768
15.
Targeting CD73 in the tumor microenvironment with MEDI9447.
Oncoimmunology
; 5(8): e1208875, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622077
16.
Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2.
Cell Cycle
; 1(6): 424-9, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12548019
17.
Cancer stem cell plasticity and tumor hierarchy.
World J Stem Cells
; 7(1): 27-36, 2015 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25621103
18.
Interleukin-6 Stimulates Defective Angiogenesis.
Cancer Res
; 75(15): 3098-107, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26081809
19.
Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer.
Cancer Res
; 75(7): 1255-64, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25670170
20.
A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways.
Mol Cancer Ther
; 14(7): 1637-49, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25948294