Detalhe da pesquisa
1.
Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
J Med Chem
; 65(1): 633-664, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34928601
2.
Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase.
Nat Commun
; 8: 15827, 2017 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28604669
3.
Identification of KasA as the cellular target of an anti-tubercular scaffold.
Nat Commun
; 7: 12581, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27581223
4.
Crystallization and initial crystallographic analysis of covalent DNA-cleavage complexes of Staphyloccocus aureus DNA gyrase with QPT-1, moxifloxacin and etoposide.
Acta Crystallogr F Struct Biol Commun
; 71(Pt 10): 1242-6, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26457513
5.
Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.
Nat Commun
; 6: 10048, 2015 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26640131
6.
The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.
J Med Chem
; 58(18): 7140-63, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26090771
7.
A multi-centre evaluation of the intra-assay and inter-assay variation of commercial and in-house anti-cardiolipin antibody assays.
Pathology
; 36(2): 182-92, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15203756
8.
Consensus guidelines on anti-cardiolipin antibody testing and reporting.
Pathology
; 36(1): 63-8, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-14757559
9.
Enabling lead discovery for histone lysine demethylases by high-throughput RapidFire mass spectrometry.
J Biomol Screen
; 17(1): 39-48, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21859681
10.
Discovery and characterization of small molecule inhibitors of the BET family bromodomains.
J Med Chem
; 54(11): 3827-38, 2011 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21568322
11.
Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance.
Nat Struct Mol Biol
; 17(9): 1152-3, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20802486