Detalhe da pesquisa
1.
Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein in testis carcinoma and other cancers: Results of a Phase I/II open-label, dose escalation study.
Int J Cancer
; 150(6): 993-1006, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34724226
2.
A Phase I/II Study of GSK525762 Combined with Fulvestrant in Patients with Hormone Receptor-positive/HER2-negative Advanced or Metastatic Breast Cancer.
Clin Cancer Res
; 30(2): 334-343, 2024 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37992310
3.
Endothelin induces rapid, dynamin-mediated budding of endothelial caveolae rich in ET-B.
J Biol Chem
; 287(21): 17353-17362, 2012 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22457360
4.
A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies.
Clin Cancer Res
; 29(4): 711-722, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350312
5.
Paediatric Strategy Forum for medicinal product development of DNA damage response pathway inhibitors in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
Eur J Cancer
; 190: 112950, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37441939
6.
Phase 2 Study of Iodine-131 Tositumomab Plus Chemotherapy in Patients With Previously Untreated Mantle-Cell Lymphoma.
Clin Lymphoma Myeloma Leuk
; 20(11): 749-756.e1, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32800518
7.
Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.
JNCI Cancer Spectr
; 4(2): pkz093, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32328561
8.
Phase I Study of the Novel Enhancer of Zeste Homolog 2 (EZH2) Inhibitor GSK2816126 in Patients with Advanced Hematologic and Solid Tumors.
Clin Cancer Res
; 25(24): 7331-7339, 2019 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471312
9.
CHOP Chemotherapy Followed by Tositumomab and Iodine-131 Tositumomab for Previously Untreated Diffuse Large B-cell Lymphoma.
Clin Lymphoma Myeloma Leuk
; 16(4): 191-6, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26832194
10.
Observational Retrospective Study of Altered Biodistribution of Tositumomab and 131I-Tositumomab.
J Nucl Med
; 56(11): 1800-3, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26338897
11.
Long-term follow-up of previously treated and treatment-naïve patients who received tositumomab and I-131 tositumomab.
Leuk Lymphoma
; 57(5): 1238-40, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26696131
12.
Patients with relapsed follicular lymphoma treated with rituximab versus tositumomab and iodine I-131 tositumomab.
Leuk Lymphoma
; 56(3): 779-81, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24898665
13.
Stimulation of polo-like kinase 3 mRNA decay by tristetraprolin.
Mol Cell Biol
; 29(8): 1999-2010, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19188452
14.
Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities.
J Biol Chem
; 280(31): 28241-50, 2005 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15946941