Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Identification of 2-Sulfonyl/Sulfonamide Pyrimidines as Covalent Inhibitors of WRN Using a Multiplexed High-Throughput Screening Assay.

Parker, Mackenzie J; Lee, Hyelee; Yao, Shihua; Irwin, Sean; Hwang, Sunil; Belanger, Kylie; de Mare, Sofia Woo; Surgenor, Richard; Yan, Lu; Gee, Patricia; Morla, Shravan; Puyang, Xiaoling; Hsiao, Peng; Zeng, Hao; Zhu, Ping; Korpal, Manav; Dransfield, Paul; Bolduc, David M; Larsen, Nicholas A.

Biochemistry ; 62(14): 2147-2160, 2023 07 18.

Artigo em Inglês | MEDLINE | ID: mdl-37403936

2.

pH Dependence of a GPR4 Selective Antagonist Hampers Its Therapeutic Potential.

Stalewski, Jacek; Shih, Amy Y; Papazyan, Romeo; Ramirez, Jocelyn; Ibanez, Gerardo; Hsiao, Peng; Yue, Yong; Yin, Jun; Badger, Calen; Wu, Shije; Ueki, Akemi; Fuchs, Bryan C; Rives, Marie-Laure.

J Pharmacol Exp Ther ; 386(1): 35-44, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37142444

3.

The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease.

Ermann, Joerg; Matmusaev, Mederbek; Haley, Emma K; Braun, Clemens; Jost, Felix; Mayer-Wrangowski, Svenja; Hsiao, Peng; Ting, Naitee; Li, Li; Terenzio, Donna; Chime, Jane; Lukas, Susan; Patnaude, Lori; Panzenbeck, Mark; Csordas, David; Zheng, Jie; Mierz, Diane; Simpson, Tom; King, F James; Klimowicz, Alex P; Mbow, M Lamine; Fine, Jay S; Miller, Craig A; Fogal, Steve E; Byrne, Fergus R.

Am J Physiol Gastrointest Liver Physiol ; 321(5): G500-G512, 2021 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-34494462

4.

Characteristics of non-smoking adult asthma patients with chronic airflow limitation.

Tay, TunnRen; Choo, Xuening; Ihsan, Rosna; Toh, Hsiao Peng; Wong, Hang Siang; Tee, Augustine.

J Asthma ; 54(10): 1026-1032, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28332897

5.

Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study.

Liu, Li; Collier, Ann C; Link, Jeanne M; Domino, Karen B; Mankoff, David A; Eary, Janet F; Spiekerman, Charles F; Hsiao, Peng; Deo, Anand K; Unadkat, Jashvant D.

Drug Metab Dispos ; 43(11): 1795-804, 2015 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-26354948

6.

Outcome of microscopic excision of a subungual glomus tumor: a 12-year evaluation.

Huang, Hsiao-Peng; Tsai, Ming-Chen; Hong, Kun-Ting; Chang, Shun-Cheng; Wang, Chih-Hsin; Li, Chun-Chang; Chiu, Wen-Kuan; Chen, Shyi-Gen.

Dermatol Surg ; 41(4): 487-92, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25782573

7.

Predicting the outer boundaries of P-glycoprotein (P-gp)-based drug interactions at the human blood-brain barrier based on rat studies.

Hsiao, Peng; Unadkat, Jashvant D.

Mol Pharm ; 11(2): 436-44, 2014 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-24364805

8.

P-glycoprotein-based loperamide-cyclosporine drug interaction at the rat blood-brain barrier: prediction from in vitro studies and extrapolation to humans.

Hsiao, Peng; Unadkat, Jashvant D.

Mol Pharm ; 9(3): 629-33, 2012 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-22316009

9.

In vitro-to-in vivo prediction of P-glycoprotein-based drug interactions at the human and rodent blood-brain barrier.

Hsiao, Peng; Bui, Tot; Ho, Rodney J Y; Unadkat, Jashvant D.

Drug Metab Dispos ; 36(3): 481-4, 2008 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-18057117

10.

Comparison of the Proportion and Healthcare Utilisation of Adult Patients with Uncontrolled Severe Asthma versus Non-Severe Asthma Seen in a Southeast Asian Hospital-Based Respiratory Specialist Clinic.

Tay, Tunn Ren; Wong, Hang Siang; Ihsan, Rosna; Toh, Hsiao Peng; Choo, Xuening; Tee, Augustine Kh.

Ann Acad Med Singap ; 46(6): 217-228, 2017 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-28733686

11.

The role of transporters in drug interactions.

Endres, Christopher J; Hsiao, Peng; Chung, Francisco S; Unadkat, Jashvant D.

Eur J Pharm Sci ; 27(5): 501-17, 2006 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-16364611

12.

Risk factors and incidence of repeat osteoporotic fractures among the elderly in Taiwan: a population-based cohort study.

Hsiao, Peng-Ching; Chen, Tzeng-Ji; Li, Chung-Yi; Chu, Chi-Ming; Su, Tung-Ping; Wang, Sheng-Hao; Pan, Hsueh-Hsing; Wang, Kwua-Yun.

Medicine (Baltimore) ; 94(7): e532, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25700317

13.

[A concept analysis of stress].

Hsiao, Peng-Ching; Tang, Yu-Ying.

Hu Li Za Zhi ; 51(3): 71-5, 2004 Jun.

Artigo em Zh | MEDLINE | ID: mdl-15211779

14.

Beyond the ITC White Paper: emerging sciences in drug transporters and opportunities for drug development.

Lai, Yurong; Hsiao, Peng.

Curr Pharm Des ; 20(10): 1577-94, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-23789952

15.

Differences in COPD patient care by primary family caregivers: an age-based study.

Hsiao, Peng-Ching; Chu, Chi-Ming; Sung, Pei-Yi; Perng, Wann-Cherng; Wang, Kwua-Yun.

PLoS One ; 9(9): e107870, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25250897

16.

Activity of P-Glycoprotein, a ß-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease.

Deo, Anand K; Borson, Soo; Link, Jeanne M; Domino, Karen; Eary, Janet F; Ke, Ban; Richards, Todd L; Mankoff, David A; Minoshima, Satoshi; O'Sullivan, Finbarr; Eyal, Sara; Hsiao, Peng; Maravilla, Ken; Unadkat, Jashvant D.

J Nucl Med ; 55(7): 1106-11, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24842892

17.

Drug interactions at the blood-brain barrier: fact or fantasy?

Eyal, Sara; Hsiao, Peng; Unadkat, Jashvant D.

Pharmacol Ther ; 123(1): 80-104, 2009 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-19393264

18.

Verapamil P-glycoprotein transport across the rat blood-brain barrier: cyclosporine, a concentration inhibition analysis, and comparison with human data.

Hsiao, Peng; Sasongko, Lucy; Link, Jeanne M; Mankoff, David A; Muzi, Mark; Collier, Ann C; Unadkat, Jashvant D.

J Pharmacol Exp Ther ; 317(2): 704-10, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16415090

19.

Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety.

Hsiao, Peng-Ching; Tang, Yu-Ying; Liaw, Wen-Jinn; Yue-Cune Chang, Ya-Hsin Lee; Chen, Fa-Chang; Wang, Kwua-Yun.

Acta Anaesthesiol Taiwan ; 44(2): 93-9, 2006 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-16845914

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