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1.
Proc Natl Acad Sci U S A ; 120(34): e2307151120, 2023 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-37579169

RESUMO

Anisotropic hopping in a toy Hofstadter model was recently invoked to explain a rich and surprising Landau spectrum measured in twisted bilayer graphene away from the magic angle. Suspecting that such anisotropy could arise from unintended uniaxial strain, we extend the Bistritzer-MacDonald model to include uniaxial heterostrain and present a detailed analysis of its impact on band structure and magnetotransport. We find that such strain strongly influences band structure, shifting the three otherwise-degenerate van Hove points to different energies. Coupled to a Boltzmann magnetotransport calculation, this reproduces previously unexplained nonsaturating [Formula: see text] magnetoresistance over broad ranges of density near filling [Formula: see text] and predicts subtler features that had not been noticed in the experimental data. In contrast to these distinctive signatures in longitudinal resistivity, the Hall coefficient is barely influenced by strain, to the extent that it still shows a single sign change on each side of the charge neutrality point-surprisingly, this sign change no longer occurs at a van Hove point. The theory also predicts a marked rotation of the electrical transport principal axes as a function of filling even for fixed strain and for rigid bands. More careful examination of interaction-induced nematic order versus strain effects in twisted bilayer graphene could thus be in order.

2.
Proc Natl Acad Sci U S A ; 119(16): e2118482119, 2022 Apr 19.
Artigo em Inglês | MEDLINE | ID: mdl-35412918

RESUMO

SignificanceWhen two sheets of graphene are twisted to the magic angle of 1.1∘, the resulting flat moiré bands can host exotic correlated electronic states such as superconductivity and ferromagnetism. Here, we show transport properties of a twisted bilayer graphene device at 1.38∘, far enough above the magic angle that we do not expect exotic correlated states. Instead, we see several unusual behaviors in the device's resistivity upon tuning both charge carrier density and perpendicular magnetic field. We can reproduce these behaviors with a surprisingly simple model based on Hofstadter's butterfly. These results shed light on the underlying properties of twisted bilayer graphene.

3.
PLoS One ; 8(10): e76224, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24116098

RESUMO

We report on a method to improve in vitro diagnostic assays that detect immune response, with specific application to HIV-1. The inherent polyclonal diversity of the humoral immune response was addressed by using sequential in situ click chemistry to develop a cocktail of peptide-based capture agents, the components of which were raised against different, representative anti-HIV antibodies that bind to a conserved epitope of the HIV-1 envelope protein gp41. The cocktail was used to detect anti-HIV-1 antibodies from a panel of sera collected from HIV-positive patients, with improved signal-to-noise ratio relative to the gold standard commercial recombinant protein antigen. The capture agents were stable when stored as a powder for two months at temperatures close to 60(o)C.


Assuntos
Anticorpos Anti-HIV/imunologia , Proteína gp41 do Envelope de HIV/imunologia , Soropositividade para HIV/imunologia , Peptídeos/imunologia , Sequência de Aminoácidos , Anticorpos Anti-Idiotípicos/imunologia , Química Click/métodos , Ensaio de Imunoadsorção Enzimática , Epitopos/imunologia , Anticorpos Anti-HIV/sangue , Infecções por HIV/sangue , Infecções por HIV/diagnóstico , Infecções por HIV/imunologia , Soropositividade para HIV/diagnóstico , Soropositividade para HIV/virologia , Humanos , Estrutura Molecular , Peptídeos/síntese química , Peptídeos/química , Ligação Proteica/imunologia , Estabilidade Proteica , Razão Sinal-Ruído , Temperatura
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