Detalhe da pesquisa
1.
Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease.
Int J Mol Sci
; 24(10)2023 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37239980
2.
Structure-based design of a novel inhibitor of the ZIKA virus NS2B/NS3 protease.
Bioorg Chem
; 128: 106109, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36049322
3.
Identification of Cysteine 270 as a Novel Site for Allosteric Modulators of SARS-CoV-2 Papain-Like Protease.
Angew Chem Int Ed Engl
; 61(52): e202212378, 2022 12 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36308706
4.
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients.
Acta Pharmacol Sin
; 41(9): 1167-1177, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737471
5.
Chemical Space Profiling of SARS-CoV-2 PLpro Using DNA-Encoded Focused Libraries.
ACS Med Chem Lett
; 15(4): 555-564, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38628804
6.
Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches.
Chem Sci
; 14(18): 4681-4696, 2023 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37181765
7.
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library.
J Med Chem
; 66(16): 11118-11132, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552553
8.
Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach.
J Med Chem
; 63(13): 7052-7065, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32459096
9.
Structure-Based Survey of the Binding Modes of BACE1 Inhibitors.
ACS Chem Neurosci
; 10(2): 880-889, 2019 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30540177