Detalhe da pesquisa
1.
Isoliquiritigenin, an Orally Available Natural FLT3 Inhibitor from Licorice, Exhibits Selective Anti-Acute Myeloid Leukemia Efficacy In Vitro and In Vivo.
Mol Pharmacol
; 96(5): 589-599, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31462456
2.
Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.
Eur J Med Chem
; 143: 1148-1164, 2018 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133048
3.
Discovery of selective protein arginine methyltransferase 5 inhibitors and biological evaluations.
Chem Biol Drug Des
; 89(4): 585-598, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27714957
4.
Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal Model.
J Med Chem
; 59(18): 8293-305, 2016 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27535613
5.
From Lead to Drug Candidate: Optimization of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as Agents for the Treatment of Triple Negative Breast Cancer.
J Med Chem
; 59(21): 9788-9805, 2016 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27739679
6.
Severe congenital hemolytic anemia caused by a novel compound heterozygous PKLR gene mutation in a Chinese boy.
Chin Med J (Engl)
; 132(1): 92-95, 2019 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30628965