Detalhe da pesquisa
1.
Transporters in Regulatory Science: Notable Contributions from Dr. Giacomini in the Past Two Decades.
Drug Metab Dispos
; 2022 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35768075
2.
Connecting Hydroxychloroquine In Vitro Antiviral Activity to In Vivo Concentration for Prediction of Antiviral Effect: A Critical Step in Treating Patients With Coronavirus Disease 2019.
Clin Infect Dis
; 71(12): 3232-3236, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435791
3.
Comparative proteomic analysis of SLC13A5 knockdown reveals elevated ketogenesis and enhanced cellular toxic response to chemotherapeutic agents in HepG2 cells.
Toxicol Appl Pharmacol
; 402: 115117, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32634519
4.
Metformin Disrupts Bile Acid Efflux by Repressing Bile Salt Export Pump Expression.
Pharm Res
; 37(2): 26, 2020 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31907698
5.
A Comparison of Pediatric and Adult Safety Studies for Antipsychotic and Antidepressant Drugs Submitted to the United States Food and Drug Administration.
J Pediatr
; 208: 236-242.e3, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30679050
6.
Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells.
J Biol Chem
; 292(33): 13890-13901, 2017 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28655760
7.
Identification and Quantitative Assessment of Uremic Solutes as Inhibitors of Renal Organic Anion Transporters, OAT1 and OAT3.
Mol Pharm
; 13(9): 3130-40, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27467266
8.
Perspectives in regulatory science: translational and clinical pharmacology.
Drug Discov Today Technol
; 21-22: 67-73, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27978990
9.
The role of bile salt export pump gene repression in drug-induced cholestatic liver toxicity.
Drug Metab Dispos
; 42(3): 318-22, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24335466
10.
Predicting nonlinear pharmacokinetics of omeprazole enantiomers and racemic drug using physiologically based pharmacokinetic modeling and simulation: application to predict drug/genetic interactions.
Pharm Res
; 31(8): 1919-29, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24590877
11.
Pharmacokinetics-Bridging Between Autoinjectors and Prefilled Syringes for Subcutaneous Injection: Case Examples Revealing a Knowledge Gap.
Clin Pharmacol Ther
; 115(3): 404-407, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38167787
12.
Clinical Pharmacology Approaches to Support Approval of New Routes of Administration for Therapeutic Proteins.
Clin Pharmacol Ther
; 115(3): 440-451, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38235832
13.
Using Machine Learning to Determine a Suitable Patient Population for Anakinra for the Treatment of COVID-19 Under the Emergency Use Authorization.
Clin Pharmacol Ther
; 115(4): 890-895, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38348530
14.
Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).
Toxicol Appl Pharmacol
; 273(1): 100-9, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24001450
15.
Model-Based Approach to Selecting Pegfilgrastim Dose for Pharmacokinetic and Pharmacodynamic Similarity Studies in Biosimilar Development.
Clin Pharmacol Ther
; 113(1): 62-70, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36000498
16.
Impact of Organ Impairment on the Pharmacokinetics of Therapeutic Peptides and Proteins.
AAPS J
; 25(4): 54, 2023 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37231199
17.
The Association Between Baseline Hepatic or Renal Function and Clinical Outcomes for Patients With Non-Small Cell Lung Cancer Treated With a PD-1/PD-L1 Blocking Antibody Using Real-World and Trial Data.
Clin Pharmacol Ther
; 113(5): 1139-1149, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790088
18.
Evaluating Pneumonitis Incidence in Patients with Non-small Cell Lung Cancer Treated with Immunotherapy and/or Chemotherapy Using Real-world and Clinical Trial Data.
Cancer Res Commun
; 3(2): 258-266, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36860658
19.
A systematic comparison of cockcroft-gault and modification of diet in renal disease equations for classification of kidney dysfunction and dosage adjustment.
Ann Pharmacother
; 46(9): 1174-87, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22932303
20.
Botanical-drug interactions: a scientific perspective.
Planta Med
; 78(13): 1400-15, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22864989