Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Long non-coding RNAs: definitions, functions, challenges and recommendations.

Mattick, John S; Amaral, Paulo P; Carninci, Piero; Carpenter, Susan; Chang, Howard Y; Chen, Ling-Ling; Chen, Runsheng; Dean, Caroline; Dinger, Marcel E; Fitzgerald, Katherine A; Gingeras, Thomas R; Guttman, Mitchell; Hirose, Tetsuro; Huarte, Maite; Johnson, Rory; Kanduri, Chandrasekhar; Kapranov, Philipp; Lawrence, Jeanne B; Lee, Jeannie T; Mendell, Joshua T; Mercer, Timothy R; Moore, Kathryn J; Nakagawa, Shinichi; Rinn, John L; Spector, David L; Ulitsky, Igor; Wan, Yue; Wilusz, Jeremy E; Wu, Mian.

Nat Rev Mol Cell Biol ; 24(6): 430-447, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36596869

2.

Gene regulation by long non-coding RNAs and its biological functions.

Statello, Luisa; Guo, Chun-Jie; Chen, Ling-Ling; Huarte, Maite.

Nat Rev Mol Cell Biol ; 22(2): 96-118, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33353982

3.

A "Counter-Enhancer" in Tumor Suppression.

Marchese, Francesco P; Huarte, Maite.

Cell ; 173(6): 1318-1319, 2018 05 31.

Artigo em Inglês | MEDLINE | ID: mdl-29856950

4.

Author Correction: Gene regulation by long non-coding RNAs and its biological functions.

Statello, Luisa; Guo, Chun-Jie; Chen, Ling-Ling; Huarte, Maite.

Nat Rev Mol Cell Biol ; 22(2): 159, 2021 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-33420484

5.

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response.

Huarte, Maite; Guttman, Mitchell; Feldser, David; Garber, Manuel; Koziol, Magdalena J; Kenzelmann-Broz, Daniela; Khalil, Ahmad M; Zuk, Or; Amit, Ido; Rabani, Michal; Attardi, Laura D; Regev, Aviv; Lander, Eric S; Jacks, Tyler; Rinn, John L.

Cell ; 142(3): 409-19, 2010 Aug 06.

Artigo em Inglês | MEDLINE | ID: mdl-20673990

6.

A Long Noncoding RNA Regulates Sister Chromatid Cohesion.

Marchese, Francesco P; Grossi, Elena; Marín-Béjar, Oskar; Bharti, Sanjay Kumar; Raimondi, Ivan; González, Jovanna; Martínez-Herrera, Dannys Jorge; Athie, Alejandro; Amadoz, Alicia; Brosh, Robert M; Huarte, Maite.

Mol Cell ; 63(3): 397-407, 2016 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-27477908

7.

Lid2 is required for coordinating H3K4 and H3K9 methylation of heterochromatin and euchromatin.

Li, Fei; Huarte, Maite; Zaratiegui, Mikel; Vaughn, Matthew W; Shi, Yang; Martienssen, Rob; Cande, W Zacheus.

Cell ; 135(2): 272-83, 2008 Oct 17.

Artigo em Inglês | MEDLINE | ID: mdl-18957202

8.

lncRNA-DNA hybrids regulate distant genes.

Mas, Aina Maria; Huarte, Maite.

EMBO Rep ; 21(3): e50107, 2020 03 04.

Artigo em Inglês | MEDLINE | ID: mdl-32078233

9.

LincRNA-p21 suppresses target mRNA translation.

Yoon, Je-Hyun; Abdelmohsen, Kotb; Srikantan, Subramanya; Yang, Xiaoling; Martindale, Jennifer L; De, Supriyo; Huarte, Maite; Zhan, Ming; Becker, Kevin G; Gorospe, Myriam.

Mol Cell ; 47(4): 648-55, 2012 Aug 24.

Artigo em Inglês | MEDLINE | ID: mdl-22841487

10.

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

Li, Li; van Breugel, Pieter C; Loayza-Puch, Fabricio; Ugalde, Alejandro Pineiro; Korkmaz, Gozde; Messika-Gold, Naama; Han, Ruiqi; Lopes, Rui; Barbera, Eric P; Teunissen, Hans; de Wit, Elzo; Soares, Ricardo J; Nielsen, Boye S; Holmstrøm, Kim; Martínez-Herrera, Dannys J; Huarte, Maite; Louloupi, Annita; Drost, Jarno; Elkon, Ran; Agami, Reuven.

Nucleic Acids Res ; 46(8): 4213-4227, 2018 05 04.

Artigo em Inglês | MEDLINE | ID: mdl-29481642

11.

The DMM complex prevents spreading of DNA methylation from transposons to nearby genes in Neurospora crassa.

Honda, Shinji; Lewis, Zachary A; Huarte, Maite; Cho, Lucy Y; David, Larry L; Shi, Yang; Selker, Eric U.

Genes Dev ; 24(5): 443-54, 2010 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-20139222

12.

Expanding the p53 regulatory network: LncRNAs take up the challenge.

Grossi, Elena; Sánchez, Yolanda; Huarte, Maite.

Biochim Biophys Acta ; 1859(1): 200-8, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-26196323

13.

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development.

Qi, Hank H; Sarkissian, Madathia; Hu, Gang-Qing; Wang, Zhibin; Bhattacharjee, Arindam; Gordon, D Benjamin; Gonzales, Michelle; Lan, Fei; Ongusaha, Pat P; Huarte, Maite; Yaghi, Nasser K; Lim, Huijun; Garcia, Benjamin A; Brizuela, Leonardo; Zhao, Keji; Roberts, Thomas M; Shi, Yang.

Nature ; 466(7305): 503-7, 2010 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-20622853

14.

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.

Guttman, Mitchell; Amit, Ido; Garber, Manuel; French, Courtney; Lin, Michael F; Feldser, David; Huarte, Maite; Zuk, Or; Carey, Bryce W; Cassady, John P; Cabili, Moran N; Jaenisch, Rudolf; Mikkelsen, Tarjei S; Jacks, Tyler; Hacohen, Nir; Bernstein, Bradley E; Kellis, Manolis; Regev, Aviv; Rinn, John L; Lander, Eric S.

Nature ; 458(7235): 223-7, 2009 Mar 12.

Artigo em Inglês | MEDLINE | ID: mdl-19182780

15.

The chromatin-associated lncREST ensures effective replication stress response by promoting the assembly of fork signaling factors.

Statello, Luisa; Fernandez-Justel, José Miguel; González, Jovanna; Montes, Marta; Ranieri, Alessia; Goñi, Enrique; Mas, Aina M; Huarte, Maite.

Nat Commun ; 15(1): 978, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-38302450

16.

Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1.

Torella, Laura; Klermund, Julia; Bilbao-Arribas, Martin; Tamayo, Ibon; Andrieux, Geoffroy; Chmielewski, Kay O; Vales, Africa; Olagüe, Cristina; Moreno-Luqui, Daniel; Raimondi, Ivan; Abad, Amaya; Torrens-Baile, Julen; Salido, Eduardo; Huarte, Maite; Hernaez, Mikel; Boerries, Melanie; Cathomen, Toni; Zabaleta, Nerea; Gonzalez-Aseguinolaza, Gloria.

EMBO Mol Med ; 16(1): 112-131, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38182795

17.

Revisiting the outcome of adult wild-type Htt inactivation in the context of HTT-lowering strategies for Huntington's disease.

Regio, Sara; Vachey, Gabriel; Goñi, Enrique; Duarte, Fabio; Rybarikova, Margareta; Sipion, Mélanie; Rey, Maria; Huarte, Maite; Déglon, Nicole.

Brain Commun ; 5(6): fcad344, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-38116140

18.

ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins.

Mas, Aina Maria; Goñi, Enrique; Ruiz de Los Mozos, Igor; Arcas, Aida; Statello, Luisa; González, Jovanna; Blázquez, Lorea; Lee, Wei Ting Chelsea; Gupta, Dipika; Sejas, Álvaro; Hoshina, Shoko; Armaos, Alexandros; Tartaglia, Gian Gaetano; Waga, Shou; Ule, Jernej; Rothenberg, Eli; Gómez, María; Huarte, Maite.

Nat Commun ; 14(1): 4447, 2023 07 24.

Artigo em Inglês | MEDLINE | ID: mdl-37488096

19.

Large non-coding RNAs: missing links in cancer?

Huarte, Maite; Rinn, John L.

Hum Mol Genet ; 19(R2): R152-61, 2010 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-20729297

20.

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression.

Khalil, Ahmad M; Guttman, Mitchell; Huarte, Maite; Garber, Manuel; Raj, Arjun; Rivea Morales, Dianali; Thomas, Kelly; Presser, Aviva; Bernstein, Bradley E; van Oudenaarden, Alexander; Regev, Aviv; Lander, Eric S; Rinn, John L.

Proc Natl Acad Sci U S A ; 106(28): 11667-72, 2009 Jul 14.

Artigo em Inglês | MEDLINE | ID: mdl-19571010

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