Detalhe da pesquisa
1.
Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase.
Proc Natl Acad Sci U S A
; 121(7): e2314085121, 2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38330013
2.
Therapy of autoimmune inflammation in sporadic amyotrophic lateral sclerosis: Dimethyl fumarate and H-151 downregulate inflammatory cytokines in the cGAS-STING pathway.
FASEB J
; 37(8): e23068, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37436778
3.
Eicosanoid regulation of debris-stimulated metastasis.
Proc Natl Acad Sci U S A
; 118(41)2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34607951
4.
Transformed cells maintain survival by downregulating autophagy at a high cell confluency.
J Cell Physiol
; 238(10): 2468-2480, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37566647
5.
Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice.
Biochem Biophys Res Commun
; 667: 64-72, 2023 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37209564
6.
Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase.
Proc Natl Acad Sci U S A
; 117(21): 11753-11759, 2020 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32398374
7.
Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation.
Proc Natl Acad Sci U S A
; 117(15): 8431-8436, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32220957
8.
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression.
Proc Natl Acad Sci U S A
; 117(35): 21576-21587, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32801214
9.
Aflatoxin B1 exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner.
Ecotoxicol Environ Saf
; 249: 114417, 2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36525946
10.
Gintonin-Induced Wound-Healing-Related Responses Involve Epidermal-Growth-Factor-like Effects in Keratinocytes.
Int J Mol Sci
; 24(18)2023 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37762395
11.
Aflatoxin B1 Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity.
Int J Mol Sci
; 24(12)2023 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37373086
12.
Paradoxical downregulation of LPAR3 exerts tumor-promoting activity through autophagy induction in Ras-transformed cells.
BMC Cancer
; 22(1): 969, 2022 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36088312
13.
Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation.
Proc Natl Acad Sci U S A
; 116(14): 7083-7088, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890645
14.
Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor.
Proc Natl Acad Sci U S A
; 116(5): 1698-1703, 2019 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30647111
15.
Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK.
Proc Natl Acad Sci U S A
; 116(11): 5154-5159, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804206
16.
Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease.
Proc Natl Acad Sci U S A
; 115(25): E5815-E5823, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735655
17.
Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation.
Proc Natl Acad Sci U S A
; 115(20): 5283-5288, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29717038
18.
Wound Healing Effect of Gintonin Involves Lysophosphatidic Acid Receptor/Vascular Endothelial Growth Factor Signaling Pathway in Keratinocytes.
Int J Mol Sci
; 22(18)2021 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34576317
19.
Effect of the Gintonin-Enriched Fraction on Glucagon-Like-Protein-1 Release.
Molecules
; 26(20)2021 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684879
20.
Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development.
Molecules
; 26(16)2021 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34443621