RESUMO
The correlation between heat production and muscular work with loads from 50 to 500 g was studied in white rats adapted to cold.
Assuntos
Adaptação Fisiológica , Temperatura Baixa , Eficiência/fisiologia , Músculos/fisiologia , Esforço Físico , Animais , Regulação da Temperatura Corporal , Estimulação Elétrica , Metabolismo Energético , Contração Isotônica , Masculino , RatosRESUMO
I. a. administration of noradrenaline (NA) activated cold receptors both in control and in cold-adapted rats. Various doses of NA induced the receptors reaction of different duration. After adaptation to cold the sensitivity of receptors to NA increased. The data obtained suggest that the sympathetic systems and the receptors sensitivity to NA play an important role in static activity of the skin cold receptors.
Assuntos
Adaptação Fisiológica/efeitos dos fármacos , Temperatura Baixa , Células Receptoras Sensoriais/efeitos dos fármacos , Pele/efeitos dos fármacos , Animais , Temperatura Corporal/efeitos dos fármacos , Relação Dose-Resposta a Droga , Masculino , Estimulação Física/métodos , Ratos , Reto , Pele/inervação , Estimulação QuímicaRESUMO
After the cold adaptation muscle contraction and the working capacity decreased. However, the muscles of the adapted to cold rats are able to save the initial power for a longer time. The muscular work of adapted to cold rats involves a greater expenditure of energy as compared with the control rats. Changes of the working capacity of skeletal muscles in control rats after noradrenalin administration are similar to those occurring in adapted to cold rats.
Assuntos
Adaptação Fisiológica , Temperatura Baixa , Músculos/fisiologia , Norepinefrina/farmacologia , Animais , Temperatura Corporal/efeitos dos fármacos , Regulação da Temperatura Corporal , Masculino , Contração Muscular/efeitos dos fármacos , RatosRESUMO
Inderal does not affect the thermoregulatory system in thermoneutral conditions. Blockade of beta-adrenoreceptors at 6 degrees C decreases the oxygen consumption in cold-acclimated rats and reduces it down to the level of control animals. Cold-acclimated rats have the same level of work hyperthermia at different ambient temperatures (26 degrees C, 6 degrees C) and under inderal injection. Control animals can only the same in warm environment.