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1.
Artif Organs ; 47(11): 1794-1797, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37587902

RESUMO

BACKGROUND: Ex vivo lung perfusion (EVLP) enables lung resuscitation before transplantation, and training is key, particularly in low-volume settings. To enable technique refinement and continuing education, we sought to demonstrate the value of a low-cost, high-fidelity EVLP simulator that would allow reproducible clinical scenarios. METHODS: In partnership with our EVLP manufacturer, we utilized the XPS™ Jensen Lung with our clinical system. The Jensen Lung has two simulated lung bladders and an in-line polymethylpentene fiber oxygenator. It allows titration of ventilator support which aids in accurate clinical simulation. For simulations, blood gases (BGs) were obtained and compared with integrated in-line perfusate gas monitors (PGMs). PaO2 , PCO2 , and pH were measured and compared. RESULTS: The PGM and BG values were not significantly different throughout the range of FiO2 and sweep gas flow rates evaluated. The "delta" PaO2 was measured between LA and PA and did not show any change between approaches. The pH measurement between BG and PGM was not significantly different. CONCLUSIONS: The XPS™ Jensen Lung simulator allows for a high-fidelity simulator of clinical EVLP. The correlation of the PGM and the BG measurement of the PaO2 and pH allow for a low-cost simulation, as the PGMs are in line in the circuit, and enable real-time tracking of perfusate gas parameters with the PGM. Implementation of a standardized clinical EVLP training program allows the maintenance of technique and enables clinical simulation training without the need for costly animal perfusions and the use of multiple BG measurements.


Assuntos
Transplante de Pulmão , Animais , Transplante de Pulmão/métodos , Pulmão , Circulação Extracorpórea/métodos , Perfusão/métodos , Gases
2.
J Cardiothorac Surg ; 11(1): 136, 2016 Aug 24.
Artigo em Inglês | MEDLINE | ID: mdl-27557530

RESUMO

BACKGROUND: As minimally invasive cardiac and vascular procedures are on the rise, the incidence of iatrogenic acute aortic dissection (IAAD) will increase. Cardiovascular professionals should be aware about the risk factors, means of prevention and best management options for IAAD in the perioperative setting. CASE PRESENTATION: We present the successful clinical management of a complicated case of IAAD after minimally invasive aortic valve replacement. CONCLUSION: High index of suspicion is required for prompt diagnosis of IAAD; collaboration of the whole perioperative team is imperative for management of this catastrophe.


Assuntos
Aneurisma Aórtico/etiologia , Dissecção Aórtica/etiologia , Insuficiência da Valva Aórtica/cirurgia , Valva Aórtica/cirurgia , Cateterismo Cardíaco/efeitos adversos , Implante de Prótese de Valva Cardíaca/métodos , Idoso , Dissecção Aórtica/diagnóstico por imagem , Dissecção Aórtica/cirurgia , Aneurisma Aórtico/diagnóstico por imagem , Aneurisma Aórtico/cirurgia , Ponte Cardiopulmonar , Oxigenação por Membrana Extracorpórea , Feminino , Humanos , Doença Iatrogênica
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