Detalhe da pesquisa
1.
Isosteric Replacement of Ester Linkage of Lysophospholipids with Heteroaromatic Rings Retains Potency and Subtype Selectivity.
Chem Pharm Bull (Tokyo)
; 71(7): 584-615, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37394607
2.
Switching Lysophosphatidylserine G Protein-Coupled Receptor Agonists to Antagonists by Acylation of the Hydrophilic Serine Amine.
J Med Chem
; 64(14): 10059-10101, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34233115
3.
Non-naturally Occurring Regio Isomer of Lysophosphatidylserine Exhibits Potent Agonistic Activity toward G Protein-Coupled Receptors.
J Med Chem
; 63(17): 9990-10029, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787112
4.
Probing the Hydrophobic Binding Pocket of G-Protein-Coupled Lysophosphatidylserine Receptor GPR34/LPS1 by Docking-Aided Structure-Activity Analysis.
J Med Chem
; 60(14): 6384-6399, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28715213
5.
Conformational Constraint of the Glycerol Moiety of Lysophosphatidylserine Affords Compounds with Receptor Subtype Selectivity.
J Med Chem
; 59(8): 3750-76, 2016 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27077565
6.
Structure-activity relationships of lysophosphatidylserine analogs as agonists of G-protein-coupled receptors GPR34, P2Y10, and GPR174.
J Med Chem
; 58(10): 4204-19, 2015 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25970039
7.
Lysophosphatidylserine analogues differentially activate three LysoPS receptors.
J Biochem
; 157(3): 151-60, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25320102
8.
GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position.
J Biochem
; 151(5): 511-8, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343749