Detalhe da pesquisa
1.
Energetics and kinetics of substrate analog-coupled staphylococcal nuclease folding revealed by a statistical mechanical approach.
Proc Natl Acad Sci U S A
; 117(33): 19953-19962, 2020 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32737158
2.
Development of novel lithocholic acid derivatives as vitamin D receptor agonists.
Bioorg Med Chem
; 27(16): 3674-3681, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31300316
3.
Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins.
J Biol Chem
; 292(3): 1052-1060, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27927989
4.
Halophilic mechanism of the enzymatic function of a moderately halophilic dihydrofolate reductase from Haloarcula japonica strain TR-1.
Extremophiles
; 21(3): 591-602, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28349498
5.
Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice.
Mol Pharmacol
; 88(2): 316-25, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25993998
6.
Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity.
Bioorg Med Chem
; 23(22): 7274-81, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26515040
7.
Crystal structures of complexes of vitamin D receptor ligand-binding domain with lithocholic acid derivatives.
J Lipid Res
; 54(8): 2206-2213, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23723390
8.
Critical roles of Asp270 and Trp273 in the α-repeat of the carbohydrate-binding module of endo-1,3-ß-glucanase for laminarin-binding avidity.
Glycoconj J
; 29(1): 77-85, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22198269
9.
Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions.
Front Mol Biosci
; 9: 908394, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35755825
10.
Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH.
Protein J
; 41(1): 71-78, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35094218
11.
Fluorescence-quenching screening of protein kinase C ligands with an environmentally sensitive fluorophore.
Bioconjug Chem
; 22(5): 923-30, 2011 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21434694
12.
Hepta-Histidine Inhibits Tau Aggregation.
ACS Chem Neurosci
; 12(16): 3015-3027, 2021 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34319089
13.
HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology.
Commun Biol
; 4(1): 1175, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635772
14.
Mutational effects of Cys113 on structural dynamics of Pin1.
Biophys Physicobiol
; 16: 452-465, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31984197
15.
Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism.
Neurobiol Aging
; 84: 240.e13-240.e22, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31027853
16.
Dual conformation of the ligand induces the partial agonistic activity of retinoid X receptor α (RXRα).
FEBS Lett
; 593(2): 242-250, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30565665
17.
A cavity with an appropriate size is the basis of the PPIase activity.
Protein Eng Des Sel
; 21(2): 83-9, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18175776
18.
2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure.
Bioorg Med Chem
; 16(14): 6949-64, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18539034
19.
An Overlapping Region between the Two Terminal Folding Units of the Outer Surface Protein A (OspA) Controls Its Folding Behavior.
J Mol Biol
; 430(12): 1799-1813, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29709572
20.
25 S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex.
J Med Chem
; 61(15): 6658-6673, 2018 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29989817