Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma.

Roddie, Claire; Lekakis, Lazaros J; Marzolini, Maria A V; Ramakrishnan, Aravind; Zhang, Yiyun; Hu, Yanqing; Peddareddigari, Vijay G R; Khokhar, Nushmia; Chen, Robert; Basilico, Silvia; Raymond, Meera; Vargas, Frederick Arce; Duffy, Kevin; Brugger, Wolfram; O'Reilly, Maeve A; Wood, Leigh; Linch, David C; Peggs, Karl S; Bachier, Carlos; Budde, Elizabeth Lihua; Lee Batlevi, Connie; Bartlett, Nancy; Irvine, David; Tholouli, Eleni; Osborne, Wendy; Ardeshna, Kirit M; Pule, Martin A.

Blood ; 141(20): 2470-2482, 2023 05 18.

Artigo em Inglês | MEDLINE | ID: mdl-36821767

2.

Critical care utilisation for patients receiving chimeric antigen receptor (CAR) T cell therapy in the UK.

Pirani, Tasneem; Wilson, Anthony; Brealey, David; Low, Ryan; O'Neill, Suzanne; Le, Jenny; Jhanji, Shaman; Bangash, Mansoor N; Mathew, Amrith; Wright, Christopher; Latif, Anne-Louise; Irvine, David; Kasipandian, Vidya; Singh, Neeraj; Saha, Rohit; Metaxa, Victoria.

Br J Anaesth ; 132(5): 1004-1006, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38521658

3.

The risk of acute liver injury associated with the use of antibiotics--evaluating robustness of results in the pharmacoepidemiological research on outcomes of therapeutics by a European consortium (PROTECT) project.

Udo, Renate; Tcherny-Lessenot, Stéphanie; Brauer, Ruth; Dolin, Paul; Irvine, David; Wang, Yunxun; Auclert, Laurent; Juhaeri, Juhaeri; Kurz, Xavier; Abenhaim, Lucien; Grimaldi, Lamiae; De Bruin, Marie L.

Pharmacoepidemiol Drug Saf ; 25 Suppl 1: 47-55, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26235335

4.

Implications of CAR-T cell therapy on apheresis services: a Scottish perspective.

Horne, Gillian A; Laird, Jennifer; Latif, Anne Louise; Irvine, David; Wilson, Matthew; Douglas, Kenneth.

J Clin Apher ; 36(3): 513-515, 2021 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-33378123

5.

Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile.

Cramer-Morales, Kimberly; Nieborowska-Skorska, Margaret; Scheibner, Kara; Padget, Michelle; Irvine, David A; Sliwinski, Tomasz; Haas, Kimberly; Lee, Jaewoong; Geng, Huimin; Roy, Darshan; Slupianek, Artur; Rassool, Feyruz V; Wasik, Mariusz A; Childers, Wayne; Copland, Mhairi; Müschen, Markus; Civin, Curt I; Skorski, Tomasz.

Blood ; 122(7): 1293-304, 2013 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-23836560

6.

The role of the bone morphogenetic proteins in leukaemic stem cell persistence.

Toofan, Parto; Irvine, David; Hopcroft, Lisa; Copland, Mhairi; Wheadon, Helen.

Biochem Soc Trans ; 42(4): 809-15, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25109962

7.

Targeting hedgehog in hematologic malignancy.

Irvine, David A; Copland, Mhairi.

Blood ; 119(10): 2196-204, 2012 Mar 08.

Artigo em Inglês | MEDLINE | ID: mdl-22223823

8.

Effective bridging therapy can improve CD19 CAR-T outcomes while maintaining safety in patients with large B-cell lymphoma.

Roddie, Claire; Neill, Lorna; Osborne, Wendy; Iyengar, Sunil; Tholouli, Eleni; Irvine, David; Chaganti, Sridhar; Besley, Caroline; Bloor, Adrian; Jones, Ceri; Uttenthal, Ben; Johnson, Rod; Sanderson, Robin; Cheok, Kathleen; Marzolini, Maria; Townsend, William; O'Reilly, Maeve; Kirkwood, Amy A; Kuhnl, Andrea.

Blood Adv ; 7(12): 2872-2883, 2023 06 27.

Artigo em Inglês | MEDLINE | ID: mdl-36724512

9.

The use of antidepressants and the risk of haemorrhagic stroke: a nested case control study.

Douglas, Ian; Smeeth, Liam; Irvine, David.

Br J Clin Pharmacol ; 71(1): 116-20, 2011 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-21143507

10.

Durable Responses and Low Toxicity After Fast Off-Rate CD19 Chimeric Antigen Receptor-T Therapy in Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia.

Roddie, Claire; Dias, Juliana; O'Reilly, Maeve A; Abbasian, Mahnaz; Cadinanos-Garai, Amaia; Vispute, Ketki; Bosshard-Carter, Leticia; Mitsikakou, Marina; Mehra, Vedika; Roddy, Harriet; Hartley, John A; Spanswick, Victoria; Lowe, Helen; Popova, Bilyana; Clifton-Hadley, Laura; Wheeler, Graham; Olejnik, Joanna; Bloor, Adrian; Irvine, David; Wood, Leigh; Marzolini, Maria A V; Domning, Sabine; Farzaneh, Farzin; Lowdell, Mark W; Linch, David C; Pule, Martin A; Peggs, Karl S.

J Clin Oncol ; 39(30): 3352-3363, 2021 10 20.

Artigo em Inglês | MEDLINE | ID: mdl-34464155

11.

CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy.

Kinstrie, Ross; Horne, Gillian A; Morrison, Heather; Irvine, David; Munje, Chinmay; Castañeda, Eduardo Gómez; Moka, Hothri A; Dunn, Karen; Cassels, Jennifer E; Parry, Narissa; Clarke, Cassie J; Scott, Mary T; Clark, Richard E; Holyoake, Tessa L; Wheadon, Helen; Copland, Mhairi.

Leukemia ; 34(6): 1613-1625, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-31896780

12.

Correction: CD93 is expressed on chronic myeloid leukemia stem cells and identifies a quiescent population which persists after tyrosine kinase inhibitor therapy.

Kinstrie, Ross; Horne, Gillian A; Morrison, Heather; Irvine, David; Munje, Chinmay; Castañeda, Eduardo Gómez; Moka, Hothri A; Dunn, Karen; Cassels, Jennifer E; Parry, Narissa; Clarke, Cassie J; Scott, Mary T; Clark, Richard E; Holyoake, Tessa L; Wheadon, Helen; Copland, Mhairi.

Leukemia ; 34(7): 1975, 2020 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-32005922

13.

High-Dose Chemotherapy in Relapsed or Refractory Metastatic Germ-Cell Cancer: The Scotland Experience.

Tan, Yun Yi; Al-Bubseeree, Bahaa; Irvine, David; MacDonald, Graham; McQuaker, Grant; Parker, Anne; Waterston, Ashita; White, Jeff.

Clin Genitourin Cancer ; 17(2): 125-131, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30563754

14.

Improved COVID-19 outcomes in CAR-T patients in the age of vaccination and preemptive pharmacotherapeutics.

Cheok, Kathleen P L; Kirkwood, Amy A; Creasey, Thomas; Tholouli, Eleni; Chaganti, Sridhar; Mathew, Amrith; Dulobdas, Vaishali; Irvine, David; Besley, Caroline; Neil, Lorna; Lown, Robert; Menne, Tobias; Townsend, William; Kuhnl, Andrea; O'Reilly, Maeve; Sanderson, Robin; Sanchez, Emilie; Roddie, Claire.

Leuk Lymphoma ; 64(12): 2037-2041, 2023 12.

Artigo em Inglês | MEDLINE | ID: mdl-37602678

15.

Severe presentations and high mortality from SARS-CoV-2 in patients undergoing chimeric antigen receptor (CAR-T) therapy: a UK NCCP analysis.

Cheok, Kathleen P L; Kirkwood, Amy A; Menne, Tobias; Tholouli, Eleni; Chaganti, Sridhar; Mathew, Amrith; Uttenthal, Ben; Russell, James; Irvine, David; Johnson, Rod; Nicholson, Emma; Bazin, Jessica; Townsend, William; Kuhnl, Andrea; O'Reilly, Maeve; Sanderson, Robin; Patel, Amit; Roddie, Claire.

Leuk Lymphoma ; 63(8): 1980-1984, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35481791

16.

Restricted access to second generation tyrosine kinase inhibitors in the UK could result in suboptimal treatment for almost half of chronic myeloid leukaemia patients: results from a West of Scotland and Lothian population study.

Gallipoli, Paolo; Shepherd, Pat; Irvine, David; Drummond, Mark; Holyoake, Tessa.

Br J Haematol ; 155(1): 128-30, 2011 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-21517814

17.

Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia.

Irvine, David A; Zhang, Bin; Kinstrie, Ross; Tarafdar, Anuradha; Morrison, Heather; Campbell, Victoria L; Moka, Hothri A; Ho, Yinwei; Nixon, Colin; Manley, Paul W; Wheadon, Helen; Goodlad, John R; Holyoake, Tessa L; Bhatia, Ravi; Copland, Mhairi.

Sci Rep ; 6: 25476, 2016 05 09.

Artigo em Inglês | MEDLINE | ID: mdl-27157927

18.

Analysis of VX nerve agent hydrolysis products in wastewater effluents by ion chromatography with amperometric and conductivity detection.

Piao, Haishan; Marx, Randall B; Schneider, Steven; Irvine, David A; Staton, John.

J Chromatogr A ; 1089(1-2): 65-71, 2005 Sep 30.

Artigo em Inglês | MEDLINE | ID: mdl-16130773

19.

Perceptions of psychosocial support groups by parents who have a child with diabetes: a needs analysis.

Creedy, Debra K; Ludlow, Tracey; Beggs, Jennie; Collis, Dianne; Irvine, David; Price, Darrell; Norton, Lyza; Cosgrove, Shelli; Houston, Kym.

Collegian ; 12(2): 28-32, 2005 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-16619910

20.

Perception and predictability of travel fatigue after long-haul flights: a retrospective study.

Flower, David J C; Irvine, David; Folkard, Simon.

Aviat Space Environ Med ; 74(2): 173-9, 2003 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-12602450

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