Detalhe da pesquisa
1.
Process Mass Intensity (PMI): A Holistic Analysis of Current Peptide Manufacturing Processes Informs Sustainability in Peptide Synthesis.
J Org Chem
; 89(7): 4261-4282, 2024 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38508870
2.
Phosphine-Dependent Photoinitiation of Alkyl Thiols under Near-UV Light Facilitates User-Friendly Peptide Desulfurization.
J Am Chem Soc
; 145(2): 1053-1061, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36602440
3.
Site-selective modification strategies in antibody-drug conjugates.
Chem Soc Rev
; 50(2): 1305-1353, 2021 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33290462
4.
In Vivo Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin Binders.
Bioconjug Chem
; 32(2): 279-289, 2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33523652
5.
Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences.
Nucleic Acids Res
; 46(5): 2218-2233, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29447373
6.
Cleavable linkers in antibody-drug conjugates.
Chem Soc Rev
; 48(16): 4361-4374, 2019 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31294429
7.
In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice.
J Pharmacol Exp Ther
; 370(3): 786-795, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936291
8.
Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production.
J Org Chem
; 84(8): 4615-4628, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30900880
9.
Bringing Macrolactamization Full Circle: Self-Cleaving Head-to-Tail Macrocyclization of Unprotected Peptides via Mild N-Acyl Urea Activation.
J Org Chem
; 84(2): 1035-1041, 2019 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30566351
10.
Spectroscopic Studies of the Chan-Lam Amination: A Mechanism-Inspired Solution to Boronic Ester Reactivity.
J Am Chem Soc
; 139(13): 4769-4779, 2017 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28266843
11.
Chan-Evans-Lam Amination of Boronic Acid Pinacol (BPin) Esters: Overcoming the Aryl Amine Problem.
J Org Chem
; 81(9): 3942-50, 2016 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27045570
12.
A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffolds.
Org Biomol Chem
; 13(15): 4570-80, 2015 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25778821
13.
Diversity-oriented synthesis of macrocyclic peptidomimetics.
Proc Natl Acad Sci U S A
; 108(17): 6793-8, 2011 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383137
14.
Characterisation of IL-23 receptor antagonists and disease relevant mutants using fluorescent probes.
Nat Commun
; 14(1): 2882, 2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37208328
15.
Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, ß-catenin, and FoxP3.
Cell Chem Biol
; 30(10): 1261-1276.e7, 2023 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591251
16.
Novel and efficient copper-catalysed synthesis of nitrogen-linked medium-ring biaryls.
Chemistry
; 17(10): 2981-6, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21290435
17.
A dual-enzyme cleavable linker for antibody-drug conjugates.
Chem Commun (Camb)
; 57(28): 3457-3460, 2021 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33687404
18.
Sulfatase-cleavable linkers for antibody-drug conjugates.
Chem Sci
; 11(9): 2375-2380, 2020 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34084399
19.
Synthesis of unprecedented scaffold diversity.
Angew Chem Int Ed Engl
; 48(7): 1194-6, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19137520
20.
MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo-allergic and anaphylactoid reactions.
Pharmacol Res Perspect
; 7(6): e00547, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31832205