Detalhe da pesquisa
1.
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides.
Proc Natl Acad Sci U S A
; 121(21): e2322923121, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38739798
2.
Accessible high-performance double nanohole tweezers.
Opt Express
; 30(3): 3760-3769, 2022 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209628
3.
Structure-Based Discovery of Lipoteichoic Acid Synthase Inhibitors.
J Chem Inf Model
; 62(10): 2586-2599, 2022 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35533315
4.
The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity.
Molecules
; 27(4)2022 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209093
5.
Probing the unfolded protein response in long-lived naked mole-rats.
Biochem Biophys Res Commun
; 529(4): 1151-1157, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32819579
6.
Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction.
Org Biomol Chem
; 18(28): 5359-5369, 2020 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32390036
7.
Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry.
Org Biomol Chem
; 17(34): 8014-8018, 2019 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31418442
8.
Context-Dependent Energetics of Loop Extensions in a Family of Tandem-Repeat Proteins.
Biophys J
; 114(11): 2552-2562, 2018 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29874606
9.
PyFolding: Open-Source Graphing, Simulation, and Analysis of the Biophysical Properties of Proteins.
Biophys J
; 114(3): 516-521, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29414697
10.
Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.
J Am Chem Soc
; 139(6): 2245-2256, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28084734
11.
A New Methodology for Incorporating Chiral Linkers into Stapled Peptides.
Chembiochem
; 18(12): 1066-1071, 2017 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28388005
12.
Nanoscale click-reactive scaffolds from peptide self-assembly.
J Nanobiotechnology
; 15(1): 70, 2017 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28985740
13.
Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer.
Angew Chem Int Ed Engl
; 56(2): 524-529, 2017 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27918136
14.
Protein stability versus function: effects of destabilizing missense mutations on BRCA1 DNA repair activity.
Biochem J
; 466(3): 613-24, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25748678
15.
Mapping the Topography of a Protein Energy Landscape.
J Am Chem Soc
; 137(46): 14610-25, 2015 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26561984
16.
Dissecting and reprogramming the folding and assembly of tandem-repeat proteins.
Biochem Soc Trans
; 43(5): 881-8, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26517898
17.
Effects of ligand binding on the mechanical properties of ankyrin repeat protein gankyrin.
PLoS Comput Biol
; 9(1): e1002864, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23341763
18.
Diffuse transition state structure for the unfolding of a leucine-rich repeat protein.
Phys Chem Chem Phys
; 16(14): 6448-59, 2014 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24535093
19.
Tandem-repeat proteins conformational mechanics are optimized to facilitate functional interactions and complexations.
Curr Opin Struct Biol
; 84: 102744, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134536
20.
Red-light modulated ortho-chloro azobenzene photoswitch for peptide stapling via aromatic substitution.
RSC Chem Biol
; 5(1): 49-54, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38179193