Assuntos
Isoniazida/administração & dosagem , Pirazinamida/administração & dosagem , Rifampina/administração & dosagem , Escarro/microbiologia , Estreptomicina/administração & dosagem , Tuberculose Pulmonar/tratamento farmacológico , Adulto , Idoso , Quimioterapia Combinada , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Mycobacterium tuberculosis , Recidiva , Tuberculose Pulmonar/microbiologiaAssuntos
Antituberculosos/administração & dosagem , Tuberculose Pulmonar/tratamento farmacológico , Adolescente , Adulto , Idoso , Antituberculosos/efeitos adversos , Quimioterapia Combinada , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva , Fatores de Tempo , Tuberculose Pulmonar/microbiologiaAssuntos
Neoplasias do Mediastino/cirurgia , Neurofibroma/cirurgia , Timoma/cirurgia , Adulto , Feminino , Humanos , MasculinoAssuntos
Oxigênio , Respiração , Testes de Função Respiratória , Tuberculose Pulmonar/fisiopatologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
Pyruvate-1-11C was prepared enzymatically by the exchange reaction of 11CO2 with the carboxyl group of pyruvic acid using pyruvate-ferredoxin oxidoreductase from Clostridium butyricum. 11C-Labeled pyruvate was purified by sublimation in specially made glassware. The radiochemical yield of pure pyruvate-1-11C was 80% 35 min after the end of bombardment. The distribution of 11C in tumor-bearing rabbits after an i.v. injection of pyruvate-1-11C was observed using a gamma camera. In contrast to normal organs, the tumor was positively visualized. We also conducted a number of successful clinical studies. A case of brain tumor which exhibited a positive image on positron-emission tomography (PET) using pyruvate-1-11C is presented.
Assuntos
Neoplasias Encefálicas/diagnóstico por imagem , Radioisótopos de Carbono , Neoplasias/diagnóstico por imagem , Piruvatos , Animais , Feminino , Humanos , Marcação por Isótopo/métodos , Masculino , Pessoa de Meia-Idade , Transplante de Neoplasias , Piruvatos/síntese química , Ácido Pirúvico , Coelhos , Cintilografia , Distribuição TecidualRESUMO
This is a report on a statistical study comparing the Kaup index and the level of tobacco consumption of patients with idiopathic spontaneous pneumothorax and those of healthy subjects. A statistically significant difference was found between the average Kaup index of the patients with idiopathic spontaneous pneumothorax and that of normal healthy individuals in Japan as published by the Ministry of Health and Welfare. A statistically significant difference was also found in the physical features between 2,433 males with idiopathic pneumothorax and 1,906 healthy males when compared by means of the Kaup index. Again, a statistically significant difference was noted in the level of tobacco consumption between the males with idiopathic pneumothorax and normal males when compared by means of the Brinkmann index. The Kaup index of idiopathic pneumothorax patients was lower than that of healthy subjects, while the level of tobacco consumption of the former was higher. Idiopathic spontaneous pneumothorax is related to thin and tall individuals and the level of tobacco consumption among such patients is higher than among healthy subjects.