Detalhe da pesquisa
1.
Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice.
Neurobiol Dis
; 192: 106422, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38286390
2.
The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites.
EMBO J
; 32(14): 2056-72, 2013 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23736259
3.
Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.
PLoS Genet
; 10(10): e1004686, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25299392
4.
Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.
PLoS Genet
; 7(12): e1002405, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22174697
5.
Metabolomic analysis of dietary-restriction-induced attenuation of sarcopenia in prematurely aging DNA repair-deficient mice.
J Cachexia Sarcopenia Muscle
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38689513
6.
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry.
PLoS Biol
; 8(4): e1000350, 2010 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20386726
7.
Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.
PLoS Biol
; 8(1): e1000283, 2010 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20098723
8.
Gene expression changes in cerebellum induced by dietary restriction.
Front Mol Neurosci
; 16: 1185665, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37293544
9.
ßCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting αCaMKII to synapses.
J Neurosci
; 31(28): 10141-8, 2011 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21752990
10.
Accelerated age-related cognitive decline and neurodegeneration, caused by deficient DNA repair.
J Neurosci
; 31(35): 12543-53, 2011 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-21880916
11.
Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health.
Front Aging Neurosci
; 14: 1095801, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36760711
12.
Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Front Aging
; 3: 1086552, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36506463
13.
The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Front Aging
; 3: 1005322, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36313181
14.
Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice.
Proc Natl Acad Sci U S A
; 105(17): 6338-43, 2008 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18430798
15.
In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration.
Acta Neuropathol Commun
; 9(1): 94, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34020718
16.
Region-specific preservation of Purkinje cell morphology and motor behavior in the ATXN1[82Q] mouse model of spinocerebellar ataxia 1.
Brain Pathol
; 31(5): e12946, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33724582
17.
Pathomechanisms of ALS8: altered autophagy and defective RNA binding protein (RBP) homeostasis due to the VAPB P56S mutation.
Cell Death Dis
; 12(5): 466, 2021 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972508
18.
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice.
Aging Cell
; 20(2): e13302, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33484480
19.
A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice.
Hum Mol Genet
; 17(18): 2849-62, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18579581
20.
Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.
Acta Neuropathol
; 120(4): 461-75, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20602234