Detalhe da pesquisa
1.
Avoiding a reproducibility crisis in regulatory toxicology-on the fundamental role of ring trials.
Arch Toxicol
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38689008
2.
Increased Cell Proliferation as a Key Event in Chemical Carcinogenesis: Application in an Integrated Approach for the Testing and Assessment of Non-Genotoxic Carcinogenesis.
Int J Mol Sci
; 24(17)2023 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37686053
3.
Use of New Approach Methodologies (NAMs) in regulatory decisions for chemical safety: Report from an EPAA Deep Dive Workshop.
Regul Toxicol Pharmacol
; 135: 105261, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36103951
4.
Analyses of Transcriptomics Cell Signalling for Pre-Screening Applications in the Integrated Approach for Testing and Assessment of Non-Genotoxic Carcinogens.
Int J Mol Sci
; 23(21)2022 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36361516
5.
Mechanistic Interrogation of Cell Transformation In Vitro: The Transformics Assay as an Exemplar of Oncotransformation.
Int J Mol Sci
; 23(14)2022 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35886950
6.
Dying for change: A roadmap to refine the fish acute toxicity test after 40 years of applying a lethal endpoint.
Ecotoxicol Environ Saf
; 223: 112585, 2021 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34365212
7.
Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications.
Int J Mol Sci
; 22(20)2021 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681626
8.
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens.
Arch Toxicol
; 94(8): 2899-2923, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32594184
9.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Regul Toxicol Pharmacol
; 118: 104789, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33035627
10.
The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro.
Carcinogenesis
; 39(7): 955-967, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29554273
11.
Environmentally induced epigenetic toxicity: potential public health concerns.
Crit Rev Toxicol
; 46(8): 676-700, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27278298
12.
The transformics assay: first steps for the development of an integrated approach to investigate the malignant cell transformation in vitro.
Carcinogenesis
; 39(7): 968, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29947756
13.
Development of a reference and proficiency chemical list for human steatosis endpoints in vitro.
Front Endocrinol (Lausanne)
; 14: 1126880, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37168981
14.
OECD workshop consensus report: Ethical considerations with respect to human derived products, specifically human serum, in OECD test guidelines.
Front Toxicol
; 5: 1140698, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923365
15.
New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens-a PARC project.
Front Toxicol
; 5: 1220998, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37492623
16.
Use of computational tools in the field of food safety.
Regul Toxicol Pharmacol
; 60(3): 354-62, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21600952
17.
Characterisation and validation of an in vitro transactivation assay based on the 22Rv1/MMTV_GR-KO cell line to detect human androgen receptor agonists and antagonists.
Food Chem Toxicol
; 152: 112206, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887398
18.
Addressing potential ethical issues regarding the supply of human-derived products or reagents in in vitro OECD Test Guidelines.
ALTEX
; 36(2): 163-176, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30785210
19.
Hazard assessment of air pollutants: The transforming ability of complex pollutant mixtures in the Bhas 42 cell model.
ALTEX
; 36(4): 623-633, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31210278
20.
Uncertainties of testing methods: What do we (want to) know about carcinogenicity?
ALTEX
; 34(2): 235-252, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27776202