Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Fourth Controlled Human Infection Model (CHIM) meeting - CHIMs in endemic countries, May 22-23, 2023.

Kapulu, Melissa; Manda-Taylor, Lucinda; Balasingam, Shobana; Means, Gary; Ayiro Malungu, Mikal; Bejon, Philip; Chi, Primus Che; Chiu, Christopher; Church, E Chandler; Correa-Oliveira, Rodrigo; Day, Nicholas; Durbin, Anna; Egesa, Moses; Emerson, Claudia; Jambo, Kondwani; Mathur, Roli; Metzger, Wolfram; Mumba, Noni; Nazziwa, Winfred; Olotu, Ally; Rodgers, Jacqueline; Sinyiza, Frank; Talaat, Kawsar; Kamerling, Ingrid; Weller, Charlie; Baay, Marc; Neels, Pieter.

Biologicals ; 85: 101747, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38350825

2.

A comparison of four epidemic waves of COVID-19 in Malawi; an observational cohort study.

Anscombe, Catherine; Lissauer, Samantha; Thole, Herbert; Rylance, Jamie; Dula, Dingase; Menyere, Mavis; Kutambe, Belson; van der Veer, Charlotte; Phiri, Tamara; Banda, Ndaziona P; Mndolo, Kwazizira S; Mponda, Kelvin; Phiri, Chimota; Mallewa, Jane; Nyirenda, Mulinda; Katha, Grace; Mwandumba, Henry; Gordon, Stephen B; Jambo, Kondwani C; Cornick, Jennifer; Feasey, Nicholas; Barnes, Kayla G; Morton, Ben; Ashton, Philip M.

BMC Infect Dis ; 23(1): 79, 2023 Feb 07.

Artigo em Inglês | MEDLINE | ID: mdl-36750921

3.

I have funds to buy reagents, but not remedies.

Jambo, Kondwani.

Nature ; 606(7915): 625, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35732771

4.

Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.

Preciado-Llanes, Lorena; Aulicino, Anna; Canals, Rocío; Moynihan, Patrick J; Zhu, Xiaojun; Jambo, Ndaru; Nyirenda, Tonney S; Kadwala, Innocent; Sousa Gerós, Ana; Owen, Siân V; Jambo, Kondwani C; Kumwenda, Benjamin; Veerapen, Natacha; Besra, Gurdyal S; Gordon, Melita A; Hinton, Jay C D; Napolitani, Giorgio; Salio, Mariolina; Simmons, Alison.

Proc Natl Acad Sci U S A ; 117(34): 20717-20728, 2020 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-32788367

5.

Defective Monocyte Enzymatic Function and an Inhibitory Immune Phenotype in Human Immunodeficiency Virus-Exposed Uninfected African Infants in the Era of Antiretroviral Therapy.

Afran, Louise; Jambo, Kondwani C; Nedi, Wilfred; Miles, David J C; Kiran, Anmol; Banda, Dominic H; Kamg'ona, Ralph; Tembo, Dumizulu; Pachnio, Annette; Nastouli, Eleni; Ferne, Brigit; Mwandumba, Henry C; Moss, Paul; Goldblatt, David; Rowland-Jones, Sarah; Finn, Adam; Heyderman, Robert S.

J Infect Dis ; 226(7): 1243-1255, 2022 09 28.

Artigo em Inglês | MEDLINE | ID: mdl-35403683

6.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Africa: Current Considerations and Future Projections.

Idoko, Olubukola T; Usuf, Effua; Okomo, Uduak; Wonodi, Chizoba; Jambo, Kondwani; Kampmann, Beate; Madhi, Shabir; Adetifa, Ifedayo.

Clin Infect Dis ; 75(Suppl 1): S136-S140, 2022 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-35749696

7.

The COVID-19 pandemic in the African continent.

Bwire, Godfrey; Ario, Alex Riolexus; Eyu, Patricia; Ocom, Felix; Wamala, Joseph F; Kusi, Kwadwo A; Ndeketa, Latif; Jambo, Kondwani C; Wanyenze, Rhoda K; Talisuna, Ambrose O.

BMC Med ; 20(1): 167, 2022 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-35501853

8.

AstraZeneca COVID-19 vaccine induces robust broadly cross-reactive antibody responses in Malawian adults previously infected with SARS-CoV-2.

Chibwana, Marah G; Moyo-Gwete, Thandeka; Kwatra, Gaurav; Mandolo, Jonathan; Hermanaus, Tandile; Motlou, Thopisang; Mzindle, Nonkululeko; Ayres, Frances; Chaponda, Mphatso; Tembo, Godwin; Mwenechanya, Percy; Mitole, Ndaona; Jassi, Chisomo; Kamng'ona, Raphael; Afran, Louise; Mzinza, David; Mwandumba, Henry C; Gordon, Stephen B; Jere, Khuzwayo; Madhi, Shabir; Moore, Penny L; Heyderman, Robert S; Jambo, Kondwani C.

BMC Med ; 20(1): 128, 2022 03 28.

Artigo em Inglês | MEDLINE | ID: mdl-35346184

9.

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1-infected human macrophages.

Boliar, Saikat; Gludish, David W; Jambo, Kondwani C; Kamng'ona, Raphael; Mvaya, Leonard; Mwandumba, Henry C; Russell, David G.

Proc Natl Acad Sci U S A ; 116(15): 7431-7438, 2019 04 09.

Artigo em Inglês | MEDLINE | ID: mdl-30918127

10.

SARS-CoV-2 exposure in Malawian blood donors: an analysis of seroprevalence and variant dynamics between January 2020 and July 2021.

Mandolo, Jonathan; Msefula, Jacquline; Henrion, Marc Y R; Brown, Comfort; Moyo, Brewster; Samon, Aubrey; Moyo-Gwete, Thandeka; Makhado, Zanele; Ayres, Frances; Motlou, Thopisang; Mzindle, Nonkululeko; Kalata, Newton; Muula, Adamson S; Kwatra, Gaurav; Nsamala, Natasha; Likaka, Andrew; Mfune, Thom; Moore, Penny L; Mbaya, Bridon; French, Neil; Heyderman, Robert S; Swarthout, Todd; Jambo, Kondwani C.

BMC Med ; 19(1): 303, 2021 11 19.

Artigo em Inglês | MEDLINE | ID: mdl-34794434

11.

New management approaches to tuberculosis in people living with HIV.

Mhango, David V; Mzinza, David T; Jambo, Kondwani C; Mwandumba, Henry C.

Curr Opin Infect Dis ; 34(1): 25-33, 2021 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-33315751

12.

Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.

Mitsi, Elena; Carniel, Beatriz; Reiné, Jesús; Rylance, Jamie; Zaidi, Seher; Soares-Schanoski, Alessandra; Connor, Victoria; Collins, Andrea M; Schlitzer, Andreas; Nikolaou, Elissavet; Solórzano, Carla; Pojar, Sherin; Hill, Helen; Hyder-Wright, Angela D; Jambo, Kondwani C; Oggioni, Marco R; De Ste Croix, Megan; Gordon, Stephen B; Jochems, Simon P; Ferreira, Daniela M.

Am J Respir Crit Care Med ; 201(3): 335-347, 2020 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-31626559

13.

Inflammatory Phenotypes Predict Changes in Arterial Stiffness Following Antiretroviral Therapy Initiation.

Kelly, Christine; Tinago, Willard; Alber, Dagmar; Hunter, Patricia; Luckhurst, Natasha; Connolly, Jake; Arrigoni, Francesca; Abner, Alejandro Garcia; Kamngona, Ralph; Sheha, Irene; Chammudzi, Mishek; Jambo, Kondwani; Mallewa, Jane; Rapala, Alicja; Heyderman, Robert S; Mallon, Patrick W G; Mwandumba, Henry; Walker, A Sarah; Klein, Nigel; Khoo, Saye.

Clin Infect Dis ; 71(9): 2389-2397, 2020 12 03.

Artigo em Inglês | MEDLINE | ID: mdl-32103268

14.

Stakeholder views on the acceptability of human infection studies in Malawi.

Kapumba, Blessings M; Jambo, Kondwani; Rylance, Jamie; Gmeiner, Markus; Sambakunsi, Rodrick; Parker, Michael; Gordon, Stephen B; Gooding, Kate.

BMC Med Ethics ; 21(1): 14, 2020 02 05.

Artigo em Inglês | MEDLINE | ID: mdl-32024497

15.

HIV-Related Arterial Stiffness in Malawian Adults Is Associated With the Proportion of PD-1-Expressing CD8+ T Cells and Reverses With Antiretroviral Therapy.

Kelly, Christine; Mwandumba, Henry C; Heyderman, Robert S; Jambo, Kondwani; Kamng'ona, Raphael; Chammudzi, Mishek; Sheha, Irene; Peterson, Ingrid; Rapala, Alicja; Mallewa, Jane; Walker, A Sarah; Klein, Nigel; Khoo, Saye.

J Infect Dis ; 219(12): 1948-1958, 2019 05 24.

Artigo em Inglês | MEDLINE | ID: mdl-30629187

16.

Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.

Mitsi, Elena; Kamng'ona, Raphael; Rylance, Jamie; Solórzano, Carla; Jesus Reiné, J; Mwandumba, Henry C; Ferreira, Daniela M; Jambo, Kondwani C.

Respir Res ; 19(1): 66, 2018 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-29669565

17.

Oral Typhoid Vaccination With Live-Attenuated Salmonella Typhi Strain Ty21a Generates Ty21a-Responsive and Heterologous Influenza Virus-Responsive CD4+ and CD8+ T Cells at the Human Intestinal Mucosa.

Pennington, Shaun H; Thompson, Ameeka L; Wright, Adam K A; Ferreira, Daniela M; Jambo, Kondwani C; Wright, Angela D; Faragher, Brian; Gilmour, Jill W; Gordon, Stephen B; Gordon, Melita A.

J Infect Dis ; 213(11): 1809-19, 2016 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-26810369

18.

Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses.

Wilburn, Kaley M; Mwandumba, Henry C; Jambo, Kondwani C; Boliar, Saikat; Solouki, Sabrina; Russell, David G; Gludish, David W.

Retrovirology ; 13(1): 55, 2016 08 11.

Artigo em Inglês | MEDLINE | ID: mdl-27515378

19.

Delayed acquisition of Plasmodium falciparum antigen-specific CD4(+) T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis.

Longwe, Herbert; Phiri, Kamija S; Mbeye, Nyanyiwe M; Gondwe, Thandile; Mandala, Wilson L; Jambo, Kondwani C.

Malar J ; 15(1): 264, 2016 05 10.

Artigo em Inglês | MEDLINE | ID: mdl-27165269

20.

Proportions of CD4+, CD8+ and B cell subsets are not affected by exposure to HIV or to Cotrimoxazole prophylaxis in Malawian HIV-uninfected but exposed children.

Longwe, Herbert; Phiri, Kamija S; Mbeye, Nyanyiwe M; Gondwe, Thandile; Jambo, Kondwani C; Mandala, Wilson L.

BMC Immunol ; 16: 50, 2015 Aug 28.

Artigo em Inglês | MEDLINE | ID: mdl-26315539

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