Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Measuring the subcellular compartmentalization of viral infections by protein complementation assay.

Fernandez, Juliette; Hassen-Khodja, Cédric; Georget, Virginie; Rose, Thierry; Jacob, Yves; Janin, Yves L; Nisole, Sébastien; Vidalain, Pierre-Olivier; Arhel, Nathalie J.

Proc Natl Acad Sci U S A ; 118(2)2021 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-33402530

2.

High seroprevalence but short-lived immune response to SARS-CoV-2 infection in Paris.

Anna, François; Goyard, Sophie; Lalanne, Ana Ines; Nevo, Fabien; Gransagne, Marion; Souque, Philippe; Louis, Delphine; Gillon, Véronique; Turbiez, Isabelle; Bidard, François-Clément; Gobillion, Aline; Savignoni, Alexia; Guillot-Delost, Maude; Dejardin, François; Dufour, Evelyne; Petres, Stéphane; Richard-Le Goff, Odile; Choucha, Zaineb; Helynck, Olivier; Janin, Yves L; Escriou, Nicolas; Charneau, Pierre; Perez, Franck; Rose, Thierry; Lantz, Olivier.

Eur J Immunol ; 51(1): 180-190, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33259646

3.

On drug discovery against infectious diseases and academic medicinal chemistry contributions.

Janin, Yves L.

Beilstein J Org Chem ; 18: 1355-1378, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36247982

4.

On Reuben G. Jones synthesis of 2-hydroxypyrazines.

Legrand, Pierre; Janin, Yves L.

Beilstein J Org Chem ; 18: 935-943, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35957750

5.

Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties.

Gagnot, Glwadys; Hervin, Vincent; Coutant, Eloi P; Goyard, Sophie; Jacob, Yves; Rose, Thierry; Hibti, Fatima Ezzahra; Quatela, Alessia; Janin, Yves L.

Chemistry ; 27(6): 2112-2123, 2021 Jan 26.

Artigo em Inglês | MEDLINE | ID: mdl-33137225

6.

Bioluminescence Profiling of NanoKAZ/NanoLuc Luciferase Using a Chemical Library of Coelenterazine Analogues.

Coutant, Eloi P; Gagnot, Glwadys; Hervin, Vincent; Baatallah, Racha; Goyard, Sophie; Jacob, Yves; Rose, Thierry; Janin, Yves L.

Chemistry ; 26(4): 948-958, 2020 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-31765054

7.

Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties.

Coutant, Eloi P; Goyard, Sophie; Hervin, Vincent; Gagnot, Glwadys; Baatallah, Racha; Jacob, Yves; Rose, Thierry; Janin, Yves L.

Org Biomol Chem ; 17(15): 3709-3713, 2019 04 10.

Artigo em Inglês | MEDLINE | ID: mdl-30882838

8.

Unnatural α-amino ethyl esters from diethyl malonate or ethyl ß-bromo-α-hydroxyiminocarboxylate.

Coutant, Eloi P; Hervin, Vincent; Gagnot, Glwadys; Ford, Candice; Baatallah, Racha; Janin, Yves L.

Beilstein J Org Chem ; 14: 2853-2860, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-30498536

9.

Synthesis of unnatural α-amino esters using ethyl nitroacetate and condensation or cycloaddition reactions.

Gagnot, Glwadys; Hervin, Vincent; Coutant, Eloi P; Desmons, Sarah; Baatallah, Racha; Monnot, Victor; Janin, Yves L.

Beilstein J Org Chem ; 14: 2846-2852, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-30498535

10.

A highly sensitive bioluminescent method for measuring allergen-specific IgE in microliter samples.

Goyard, Sophie; Balbino, Bianca; Chinthrajah, Rebecca S; Lyu, Shu-Chen; Janin, Yves L; Bruhns, Pierre; Poncet, Pascal; Galli, Stephen J; Nadeau, Kari C; Reber, Laurent L; Rose, Thierry.

Allergy ; 75(11): 2952-2956, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32407549

11.

Synthetic Routes to Coelenterazine and Other Imidazo[1,2-a]pyrazin-3-one Luciferins: Essential Tools for Bioluminescence-Based Investigations.

Coutant, Eloi P; Janin, Yves L.

Chemistry ; 21(48): 17158-71, 2015 Nov 23.

Artigo em Inglês | MEDLINE | ID: mdl-26403487

12.

On the origins of SARS-CoV-2 main protease inhibitors.

Janin, Yves L.

RSC Med Chem ; 15(1): 81-118, 2024 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-38283212

13.

Biophysical analysis of Gaussia luciferase bioluminescence mechanisms using a non-oxidizable coelenterazine.

Takatsu, Kyoko; Kobayashi, Naohiro; Wu, Nan; Janin, Yves L; Yamazaki, Toshio; Kuroda, Yutaka.

BBA Adv ; 3: 100068, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37082267

14.

Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.

Nemergut, Michal; Pluskal, Daniel; Horackova, Jana; Sustrova, Tereza; Tulis, Jan; Barta, Tomas; Baatallah, Racha; Gagnot, Glwadys; Novakova, Veronika; Majerova, Marika; Sedlackova, Karolina; Marques, Sérgio M; Toul, Martin; Damborsky, Jiri; Prokop, Zbynek; Bednar, David; Janin, Yves L; Marek, Martin.

Nat Commun ; 14(1): 7864, 2023 Nov 29.

Artigo em Inglês | MEDLINE | ID: mdl-38030625

15.

Non-quinolone inhibitors of bacterial type IIA topoisomerases: a feat of bioisosterism.

Mayer, Claudine; Janin, Yves L.

Chem Rev ; 114(4): 2313-42, 2014 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-24313284

16.

A Bioluminescent 3CL^Pro Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors.

Mathieu, Cyrille; Touret, Franck; Jacquemin, Clémence; Janin, Yves L; Nougairède, Antoine; Brailly, Manon; Mazelier, Magalie; Décimo, Didier; Vasseur, Virginie; Hans, Aymeric; Valle-Casuso, José-Carlos; de Lamballerie, Xavier; Horvat, Branka; André, Patrice; Si-Tahar, Mustapha; Lotteau, Vincent; Vidalain, Pierre-Olivier.

Viruses ; 13(9)2021 09 12.

Artigo em Inglês | MEDLINE | ID: mdl-34578395

17.

5-Iodo-3-ethoxypyrazoles: an entry point to new chemical entities.

Guillou, Sandrine; Janin, Yves L.

Chemistry ; 16(15): 4669-77, 2010 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-20333718

18.

Preparation and chemistry of 3/5-halogenopyrazoles.

Janin, Yves L.

Chem Rev ; 112(7): 3924-58, 2012 Jul 11.

Artigo em Inglês | MEDLINE | ID: mdl-22548590

19.

Maximizing binary interactome mapping with a minimal number of assays.

Choi, Soon Gang; Olivet, Julien; Cassonnet, Patricia; Vidalain, Pierre-Olivier; Luck, Katja; Lambourne, Luke; Spirohn, Kerstin; Lemmens, Irma; Dos Santos, Mélanie; Demeret, Caroline; Jones, Louis; Rangarajan, Sudharshan; Bian, Wenting; Coutant, Eloi P; Janin, Yves L; van der Werf, Sylvie; Trepte, Philipp; Wanker, Erich E; De Las Rivas, Javier; Tavernier, Jan; Twizere, Jean-Claude; Hao, Tong; Hill, David E; Vidal, Marc; Calderwood, Michael A; Jacob, Yves.

Nat Commun ; 10(1): 3907, 2019 08 29.

Artigo em Inglês | MEDLINE | ID: mdl-31467278

20.

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial.

Alvey, Luke; Prado, Soizic; Huteau, Valérie; Saint-Joanis, Brigitte; Michel, Sylvie; Koch, Michel; Cole, Stewart T; Tillequin, François; Janin, Yves L.

Bioorg Med Chem ; 16(17): 8264-72, 2008 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-18752967

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Measuring the subcellular compartmentalization of viral infections by protein complementation assay.

High seroprevalence but short-lived immune response to SARS-CoV-2 infection in Paris.

On drug discovery against infectious diseases and academic medicinal chemistry contributions.

On Reuben G. Jones synthesis of 2-hydroxypyrazines.

Core-Modified Coelenterazine Luciferin Analogues: Synthesis and Chemiluminescence Properties.

Bioluminescence Profiling of NanoKAZ/NanoLuc Luciferase Using a Chemical Library of Coelenterazine Analogues.

Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties.

Unnatural α-amino ethyl esters from diethyl malonate or ethyl ß-bromo-α-hydroxyiminocarboxylate.

Synthesis of unnatural α-amino esters using ethyl nitroacetate and condensation or cycloaddition reactions.

A highly sensitive bioluminescent method for measuring allergen-specific IgE in microliter samples.

Synthetic Routes to Coelenterazine and Other Imidazo[1,2-a]pyrazin-3-one Luciferins: Essential Tools for Bioluminescence-Based Investigations.

On the origins of SARS-CoV-2 main protease inhibitors.

Biophysical analysis of Gaussia luciferase bioluminescence mechanisms using a non-oxidizable coelenterazine.

Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.

Non-quinolone inhibitors of bacterial type IIA topoisomerases: a feat of bioisosterism.

A Bioluminescent 3CL^Pro Activity Assay to Monitor SARS-CoV-2 Replication and Identify Inhibitors.

5-Iodo-3-ethoxypyrazoles: an entry point to new chemical entities.

Preparation and chemistry of 3/5-halogenopyrazoles.

Maximizing binary interactome mapping with a minimal number of assays.

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial.