Detalhe da pesquisa
1.
Efficacy and Safety of Panitumumab in Patients With RAF/RAS-Wild-Type Glioblastoma: Results From the Drug Rediscovery Protocol.
Oncologist
; 29(5): 431-440, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38109296
2.
Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D-CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials.
Int J Cancer
; 153(7): 1413-1422, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37424386
3.
Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.
BMC Cancer
; 23(1): 205, 2023 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870947
4.
Towards diagnostic criteria for malignant deep penetrating melanocytic tumors using single nucleotide polymorphism array and next-generation sequencing.
Mod Pathol
; 35(8): 1110-1120, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35184152
5.
Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2.
Gastroenterology
; 155(3): 844-851, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29758216
6.
Distinct Patterns of Somatic Mosaicism in the APC Gene in Neoplasms From Patients With Unexplained Adenomatous Polyposis.
Gastroenterology
; 152(3): 546-549.e3, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27816598
7.
Trastuzumab plus pertuzumab for HER2-amplified advanced colorectal cancer: Results from the drug rediscovery protocol (DRUP).
Eur J Cancer
; 202: 113988, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471288
8.
Efficacy of pembrolizumab and biomarker analysis in patients with WGS-based intermediate to high tumor mutational load: results from the Drug Rediscovery Protocol.
Clin Cancer Res
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38630551
9.
BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma.
JCO Precis Oncol
; 6: e2200018, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-36130145
10.
FAIR Genomes metadata schema promoting Next Generation Sequencing data reuse in Dutch healthcare and research.
Sci Data
; 9(1): 169, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35418585
11.
Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.
Clin Cancer Res
; 28(7): 1402-1411, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35046062
12.
Genome-wide copy number variations as molecular diagnostic tool for cutaneous intermediate melanocytic lesions: a systematic review and individual patient data meta-analysis.
Virchows Arch
; 479(4): 773-783, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851238
13.
Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types.
Clin Cancer Res
; 27(22): 6106-6114, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34475104
14.
Novel candidates in early-onset familial colorectal cancer.
Fam Cancer
; 19(1): 1-10, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31555933
15.
The complexity of screening PMS2 in DNA isolated from formalin-fixed paraffin-embedded material.
Eur J Hum Genet
; 28(3): 333-338, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31616036
16.
Excluding Lynch syndrome in a female patient with metachronous DNA mismatch repair deficient colon- and ovarian cancer.
Fam Cancer
; 17(3): 415-420, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29124495
17.
Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.
PLoS One
; 11(6): e0157381, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27300758
18.
Splicing analysis for exonic and intronic mismatch repair gene variants associated with Lynch syndrome confirms high concordance between minigene assays and patient RNA analyses.
Mol Genet Genomic Med
; 3(4): 327-45, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26247049